Results 161 to 170 of about 480,706 (316)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

GWAS Procedures for Gene Mapping in Diverse Populations With Complex Structures. [PDF]

Bio Protoc
Zuo Z, Li M, Liu D, Li Q, Huang B, Ye G, Wang J, Tang Y, Zhang Z.   +8 more
europepmc   +1 more source

Genomic organization and chromosomal mapping of the mouse P-cadherin gene

, 1991
Masayuki Hatta, Seiji Miyatani, Neal G. Copeland, Debra J. Gilbert, Nancy A. Jenkins, Masatoshi Takeichi   +5 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Gene mapping and candidate gene analysis of a sorghum sheathed panicle-I mutant. [PDF]

Plant Genome
Ao J, Wang R, Li W, Ding Y, Xu J, Cao N, Gao X, Cheng B, Zhao D, Zhang L.   +9 more
europepmc   +1 more source

Mapping Genes that Contribute to Daunorubicin-Induced Cytotoxicity [PDF]

, 2007
Shiwei Duan, Wasim K. Bleibel, R. Stephanie Huang, Sunita J. Shukla, Xiaolin Wu, Judith A. Badner, M. Eileen Dolan   +6 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Gene Mapping and Molecular Marker Development for Controlling Purple-Leaf Trait in Pakchoi (<i>Brassica rapa</i> subsp. <i>chinensis</i> (L.) Hanelt). [PDF]

Genes (Basel)
Song B, Yang Q, Zhang W, Yang X, Zhang L, Ouyang L, He L, Chen L, Jing Z, Huang T, Xu H, Li Y, Yang Q.   +12 more
europepmc   +1 more source

Gene mapping and functional annotation of GWAS of oral ulcers using FUMA software. [PDF]

Sci Rep, 2020
Jin X, Wang Y, Zhang X, Zhang W, Wang H, Chen C.   +5 more
europepmc   +1 more source

Using Breeding Populations With a Dual Purpose: Cultivar Development and Gene Mapping-A Case Study Using Resistance to Common Bacterial Blight in Dry Bean (Phaseolus vulgaris L.). [PDF]

Front Plant Sci, 2021
Simons KJ, Oladzad A, Lamppa R, Maniruzzaman, McClean PE, Osorno JM, Pasche JS.   +6 more
europepmc   +1 more source