Results 91 to 100 of about 284,816 (301)

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé, Caulin, Carlos, Chabaud, Sylvie, Foy, Jean-Philippe, Goudot, Patrick, Hong, Waun Ki, Lachuer, Joël, Lang, Wenhua, Lavergne, Emilie, Le Texier, Vincent, Lippman, Scott M, Perol, David, Saintigny, Pierre, Thomas, Emilie, Tortereau, Antonin   +14 more
core   +1 more source

HGNC nomenclature for fusion genes [PDF]

Leukemia, 2021
Robert Peter Gale, Andreas Hochhaus, Nicholas C. P. Cross, Christine J. Harrison   +3 more
openaire   +2 more sources

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Primary Coenzyme Q10 Deficiency [PDF]

, 2017
open4siCLINICAL CHARACTERISTICS: Primary coenzyme Q10 (CoQ10) deficiency is usually associated with multisystem involvement, including neurologic manifestations such as fatal neonatal encephalopathy with hypotonia; a late-onset slowly progressive ...
Doimo, Mara, Navas, P., Salviati, Leonardo, Trevisson, Eva   +3 more
core  

Evolution of asexual and sexual reproduction in the aspergilli [PDF]

, 2018
Aspergillus nidulans has long-been used as a model organism to gain insights into the genetic basis of asexual and sexual developmental processes both in other members of the genus Aspergillus, and filamentous fungi in general.
Chen, W., Cánovas López, David, Dyer, P.S., Eagle, C.E., Gutiérrez Pozo, Gabriel, Huang, Z., Jia, W.L., Ojeda López, M., Park, H.S., Swilaiman, S.S., Yu, J.H.   +10 more
core   +2 more sources

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Naming 'junk': Human non-protein coding RNA (ncRNA) gene nomenclature

Human Genomics, 2011
Previously, the majority of the human genome was thought to be 'junk' DNA with no functional purpose. Over the past decade, the field of RNA research has rapidly expanded, with a concomitant increase in the number of non-protein coding RNA (ncRNA) genes ...
Wright Mathew W, Bruford Elspeth A
doaj   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

Myosin-I nomenclature. [PDF]

, 2001
We suggest that the vertebrate myosin-I field adopt a common nomenclature system based on the names adopted by the Human Genome Organization (HUGO). At present, the myosin-I nomenclature is very confusing; not only are several systems in use, but several
Albanesi, JP, Bahler, M, Bement, WM, Berg, JS, Burgess, DR, Burnside, B, Cheney, RE, Corey, DP, Coudrier, E, de Lanerolle, P, Gillespie, PG, Hammer, JA, Hasson, T, Holt, JR, Hudspeth, AJ, Ikebe, M, Kendrick-Jones, J, Korn, ED, Li, R, Mercer, JA, Milligan, RA, Mooseker, MS, Ostap, EM, Petit, C, Pollard, TD, Sellers, JR, Soldati, T, Titus, MA   +27 more
core  

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source