Results 91 to 100 of about 282,097 (292)

Deciphering a cryptic minefield: A guide to Cryptosporidium gp60 subtyping

open access: yesCurrent Research in Parasitology and Vector-Borne Diseases
For 25 years, analysis of the gp60 gene has been the cornerstone of Cryptosporidium subtyping, particularly for Cryptosporidium hominis and Cryptosporidium parvum, during population-based and epidemiological studies.
Guy Robinson   +6 more
doaj   +1 more source

Experimental-confirmation and functional-annotation of predicted proteins in the chicken genome

open access: yesBMC Genomics, 2007
Background The chicken genome was sequenced because of its phylogenetic position as a non-mammalian vertebrate, its use as a biomedical model especially to study embryology and development, its role as a source of human disease organisms and its ...
McCarthy Fiona M   +2 more
doaj   +1 more source

HGNC nomenclature for fusion genes [PDF]

open access: yesLeukemia, 2021
Robert Peter Gale   +3 more
openaire   +2 more sources

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura   +4 more
wiley   +1 more source

Primary Coenzyme Q10 Deficiency [PDF]

open access: yes, 2017
open4siCLINICAL CHARACTERISTICS: Primary coenzyme Q10 (CoQ10) deficiency is usually associated with multisystem involvement, including neurologic manifestations such as fatal neonatal encephalopathy with hypotonia; a late-onset slowly progressive ...
Doimo, Mara   +3 more
core  

p63 in Mytilus galloprovincialis and p53 family members in the phylum Mollusca [PDF]

open access: yes, 2009
Genes of the p53 family are known to be critical regulators of the cell cycle. They have already been established as possible biomarkers. Elaborate regulation mechanisms result in numerous cDNA and protein isoforms being expressed from each gene of the ...
Baričević, Ana   +6 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Naming 'junk': Human non-protein coding RNA (ncRNA) gene nomenclature

open access: yesHuman Genomics, 2011
Previously, the majority of the human genome was thought to be 'junk' DNA with no functional purpose. Over the past decade, the field of RNA research has rapidly expanded, with a concomitant increase in the number of non-protein coding RNA (ncRNA) genes ...
Wright Mathew W, Bruford Elspeth A
doaj   +1 more source

Day-to-day dynamics of commensal Escherichia coli in Zimbabwean cows evidence temporal fluctuations within a host-specific population structure [PDF]

open access: yes, 2017
To get insights into the temporal pattern of commensal Escherichia coli populations, we sampled the feces of four healthy cows from the same herd in the Hwange District of Zimbabwe daily over 25 days. The cows had not received antibiotic treatment during
Andremont, Antoine   +9 more
core   +1 more source

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

open access: yesAdvanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu   +12 more
wiley   +1 more source

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