Results 91 to 100 of about 2,715,906 (243)

The case for standardizing gene nomenclature in vertebrates. [PDF]

Nature, 2023
McCarthy FM, Jones TEM, Kwitek AE, Smith CL, Vize PD, Westerfield M, Bruford EA.   +6 more
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Reply to: The case for standardizing gene nomenclature in vertebrates. [PDF]

Nature, 2023
Theofanopoulou C, Jarvis ED.
europepmc   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Selenoprotein Gene Nomenclature

, 2019
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Driscoll, Donna, Hatfield, Dolph, Hesketh, John, Diamond, Alan, Burk, Raymond, Schweizer, Ulrich, Gladyshev, Vadim, Simonović, Miljan, Rayman, Margaret, Zhang, Yan, Kim, Hwa-Young, Prabhu, K. Sandeep, Ursini, Fulvio, Conrad, Marcus, Carlson, Bradley, Copeland, Paul, Berry, Marla, Lescure, Alain, Mariotti, Marco, Sunde, Roger, Huang, Kaixun, Bruford, Elspeth, Holmgren, Arne, Lobanov, Alexei, Ferreiro, Ana, Loscalzo, Joseph, Arnér, Elias S., Brigelius-Flohé, Regina, Maiorino, Matilde, Castellano, Sergi, Lei, Xin Gen, Howard, Michael, Whanger, Philip, Salinas, Gustavo, Krol, Alain, Köhrle, Josef, Schomburg, Lutz, Liu, Qiong, Lee, Byung Cheon, Hondal, Robert, Lee, Byeong Jae, Tweedie, Susan, Hoffmann, Peter, Chavatte, Laurent, Handy, Diane, Kim, Ick Young, Tsuji, Petra, Schmidt, Edward, Guigó, Roderic, Flohé, Leopold, Kryukov, Gregory, Green, Fiona, Rozovsky, Sharon   +52 more
core   +1 more source

Third party data gene data set of eutherian growth hormone genes

Genomics Data, 2015
Among 146 potential coding sequences, the most comprehensive eutherian growth hormone gene data set annotated 100 complete coding sequences. The eutherian comparative genomic analysis protocol first described 5 major gene clusters of eutherian growth ...
Marko Premzl
doaj   +1 more source

A State‐Gated Metallo‐DNAzyme Framework Programs Tumor Stress Vulnerability Through Metabolic Licensing

Advanced Science, EarlyView.
A tumor‐state‐gated metallo‐DNAzyme framework integrates miR‐21/APE1‐responsive GLUT1 silencing with Ca/Cu‐partitioned metal–nucleic acid assembly and cystine loading. The framework first weakens glucose‐dependent metabolic buffering and then amplifies copper‐ and disulfide‐associated stress, converting tumor metabolic adaptation into programmable ...
Xiaodong Ma, Lingyun He, Xinru Wang, Yuanyuan Wei, Chengcheng Li, Jiaqi Yan, Weijian Sun, Xian Shen, Hongbo Zhang   +8 more
wiley   +1 more source

Genomic organization, expression analysis, and chromosomal localization of the mouse PEX3 gene encoding a peroxisomal assembly protein [PDF]

, 2000
The peroxin Pex3p has been identified as an integral peroxisomal membrane protein in yeast where pex3 mutants lack peroxisomal remnant structures.
Muntau, Anja C., Muntau, AC, Mayerhofer, Peter U., Albet, Sabrina, Bugaut, Maurice, Bugaut, M, Mayerhofer, PU, Roscher, AA, Albet, S, Kammerer, S, Schmid, Thomas E., Roscher, Adelbert A., Kammerer, Stefan, Schmid, TE   +13 more
core   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions. [PDF]

Leukemia, 2021
Bruford EA, Antonescu CR, Carroll AJ, Chinnaiyan A, Cree IA, Cross NCP, Dalgleish R, Gale RP, Harrison CJ, Hastings RJ, Huret JL, Johansson B, Le Beau M, Mecucci C, Mertens F, Verhaak R, Mitelman F.   +16 more
europepmc   +1 more source