Results 261 to 270 of about 463,290 (301)

Integrating Ontological Information about Genes

2014 IEEE 23rd International WETICE Conference, 2014
With the advent of biological ontologies an increasing amount of methods are emerging for enriching gene information by means of their annotations. However, problems occur in assessing semantic similarity over genetic aspects that are represented independently in different schemas when, in reality, they are not.
DESSI, NICOLETTA, Pascariello E, PES, BARBARA   +2 more
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Gene multifunctionality scoring using gene ontology

Journal of Bioinformatics and Computational Biology, 2018
Multifunctional genes are important genes because of their essential roles in human cells. Studying and analyzing multifunctional genes can help understand disease mechanisms and drug discovery. We propose a computational method for scoring gene multifunctionality based on functional annotations of the target gene from the Gene Ontology. The method is
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Methods for Gene Ontology Annotation

2007
The Gene Ontology (GO) is an established dynamic and structured vocabulary that has been successfully used in gene and protein annotation. Designed by biologists to improve data integration, GO attempts to replace the multiple nomenclatures used by specialised and large biological knowledgebases.
Emily, Dimmer, Tanya Z, Berardini, Daniel, Barrell, Evelyn, Camon   +3 more
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The ontology of the gene ontology.

AMIA ... Annual Symposium proceedings. AMIA Symposium, 2004
The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases.
Barry, Smith, Jennifer, Williams, Steffen, Schulze-Kremer   +2 more
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Gene function prediction with knowledge from gene ontology

International Journal of Data Mining and Bioinformatics, 2015
Gene function prediction is an important problem in bioinformatics. Due to the inherent noise existing in the gene expression data, the attempt to improve the prediction accuracy resorting to new classification techniques is limited. With the emergence of Gene Ontology (GO), extra knowledge about the gene products can be extracted from GO and ...
Ying, Shen, Lin, Zhang
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Application of Gene Ontology to Gene Identification

2011
Candidate gene identification deals with associating genes to underlying biological phenomena, such as diseases and specific disorders. It has been shown that classes of diseases with similar phenotypes are caused by functionally related genes. Currently, a fair amount of knowledge about the functional characterization can be found across several ...
Hugo P, Bastos, Bruno, Tavares, Catia, Pesquita, Daniel, Faria, Francisco M, Couto   +4 more
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Gene Ontology Rewritten for Computing Gene Functional Similarity

2010 International Conference on Complex, Intelligent and Software Intensive Systems, 2010
Discovery biological organisation of the cell in modules network is a challenging task. Currently, approaches based on a controlled vocabulary, as Gene Ontology, to identify the function similarity among a pair of genes have developed. We present RGO: a rewriting of the GO aiming at obtaining a more compact and informative ontology, leading to closer ...
VISCONTI, ALESSIA, CORDERO, Francesca, BOTTA, Marco, CALOGERO, Raffaele Adolfo   +3 more
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CARDIOVASCULAR GENE ONTOLOGY INITIATIVE

Atherosclerosis Supplements, 2008
Gene Ontology (GO) provides a systematic language for the description of attributes of genes and gene products in three key domains Providing full gene ontology annotation to genes associated with cardiovascular processes Ruth Lovering1, Varsha Khodiyar1, Daniel Barrell2, Emily Dimmer2, Pete Scambler3, Mike Hubank4, Rolf Apweiler2, Philippa Talmud1 ...
R. Lovering, P. Scambler, M. Hubank, R. Apweiler, P.J. Talmud   +4 more
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Gene Regulatory Networks from Gene Ontology

2013
Gene Ontology (GO) provides a controlled vocabulary and hierarchy of terms to facilitate the annotation of gene functions and molecular attributes. Given a set of genes, a Gene Ontology Network (GON) can be constructed from the corresponding GO annotations and semantic relations among GO terms.
Wenting Liu, Kuiyu Chang, Jie Zheng, Jain Divya, Jung-Jae Kim, Jagath C. Rajapakse   +5 more
openaire   +1 more source

A systematic review of ontology use in E-Learning recommender system

Computers and Education Artificial Intelligence, 2022
Nur W Rahayu
exaly