Results 141 to 150 of about 3,013,569 (257)

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

open access: yesAdvanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen   +12 more
wiley   +1 more source

Detection of Myoglobin Gene Polymorphism Associated With Pigeons' Growth Traits. [PDF]

open access: yesAnim Genet
Liao Z   +9 more
europepmc   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Interactions between single nucleotide polymorphism of SERPINA1 gene and smoking in association with COPD: a case–control study

open access: yes, 2017
Xiaowei Deng,1 Cun-hua Yuan,1 De Chang2 1Health Medical Center, 2Department of Respiratory Medicine, General Hospital of Chinese People’s Armed Police Forces, Beijing, People’s Republic of China Background: SERPINA1 gene has been implicated
Yuan CH, Chang D, Deng XW
core  

The Effect on Vitamin D Levels and VDR Gene Polymorphism on Clinical Outcomes in Asthma. [PDF]

open access: yesMed Princ Pract
Aksu GD   +6 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He   +10 more
wiley   +1 more source

Association between leptin gene rs7799039 polymorphism and lipid profile changes induced by isotretinoin treatment in acne patients

open access: yes, 2018
Omar F Khabour,1,2 Karem H Alzoubi,3 Abdul Samad Firoz,1,4 Rafat MM Al-Awad2 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, Saudi Arabia; 2Department of Medical Laboratory Sciences, Jordan ...
Al-Awad RMM   +3 more
core  

The Impact of Surfactant Protein-D Gene Polymorphism on COVID-19 Clinical Outcomes. [PDF]

open access: yesImmun Inflamm Dis
Kolsari NN   +5 more
europepmc   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

open access: yesAdvanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu   +3 more
wiley   +1 more source

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