Results 121 to 130 of about 758,578 (355)

CTLA4 gene polymorphism and autoimmunity

open access: yesImmunological Reviews, 2005
Summary:  CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA4) are two receptors that have critical but opposing functions in T‐cell stimulation. CD28 promotes a number of T‐cell activities, whereas in contrast CTLA4 is an essential inhibitor of T‐cell responses.
Gough, S, Walker, L, Sansom, D
openaire   +2 more sources

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms

open access: yesAdvanced Materials, EarlyView.
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Siwen Sun   +4 more
wiley   +1 more source

The Correlation between the CLEC16A Gene and Genetic Susceptibility to Type 1 Diabetes in Chinese Children

open access: yesInternational Journal of Endocrinology, 2012
Objective. The CLEC16A gene is related to the genetic susceptibility to T1DM with racial variability. This study investigated the association between CLEC16A gene polymorphisms and T1DM in Chinese children. Methods.
Yanmei Sang, Wei Zong, Jie Yan, Min Liu
doaj   +1 more source

Programmable Dimensional Lithography with Digital Micromirror Devices for Multifunctional Microarchitectures

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores recent advances in digital micromirror device (DMD)‐based lithography, focusing on its programmable light modulation, multi‐material compatibility, and dimensional patterning strategies. It highlights innovations from optical system design to materials integration and multifunctional applications, positioning DMD lithography as a ...
Yubin Lee   +5 more
wiley   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

open access: yesAdvanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei   +5 more
wiley   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease [PDF]

open access: bronze, 2004
Édouard Louis   +10 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Frontal-Limbic White Matter Pathway Associations with the Serotonin Transporter Gene Promoter Region (5-HTTLPR) Polymorphism [PDF]

open access: bronze, 2009
Jennifer Pacheco   +5 more
openalex   +1 more source

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