Results 171 to 180 of about 758,578 (355)

Interleukin-18 gene promoter 607A polymorphism, but not 137C polymorphism, is a protective factor for ischemic stroke in the Chinese population: A meta-analysis

, 2016
Mingjie Zhang, Yi Zhou, Xu Wang, Chen Xue, Yan Pi, Lu Guo, Chang‐Yue Gao, Jingcheng Li, Lili Zhang   +8 more
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Combined Effects of the Glutathione S-transferase P1 (GST-P1) Gene Polymorphism and Environmental Tobacco Smoke (ETS) Exposure on the Development of Asthma [PDF]

, 2006
K.T. Shair, Jocelyn M. Biagini, Grace K. LeMasters, David I. Bernstein, James E. Lockey, Gurjit K. Khurana Hershey   +5 more
openalex   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Association between ERCC1 and ERCC2 gene polymorphisms and susceptibility to pancreatic cancer

, 2016
Mei-ying He, Kang Zheng, Daniel S.W. Tan, Z.X. Wang   +3 more
openalex   +1 more source

Characterization of Exon 3 of PROP1 gene and Screening of H173R polymorphism in Karan Fries bulls [PDF]

, 2016
M. R. Vineeth, I. D. Gupta, Archana Verma, Ankit Magotra, Rakesh Kumar, Nishant Verma, Santosh Kumari   +6 more
openalex   +1 more source

Association Between BsmI Vitamin D Receptor Gene Polymorphism and Clinicopathological Features of Colorectal Cancer Patients in 2019-2020 at Prof. Dr. I.G.N.G Ngoerah Denpasar Bali

, 2023
Nadia Carolina Notoprawiro, Ni Made Desak Wihandani, I Wayan Juli Sumadi   +2 more
openalex   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

TNFAIP3 Gene Polymorphisms and the Risk of Thrombocytopenia: A Cross-Sectional Study in Iranian Population. [PDF]

Health Sci Rep
Alizadeh Saadooni S, Eftekhar Z, Jalali Far MA, Saki N, Kydani GA, Karimpourian H, Aminasnafi A.   +6 more
europepmc   +1 more source

Relationship Between IL-10 Gene Polymorphism and Spinal Tuberculosis

, 2019
Jinming Ma, Zhongzhe Lv, Jianchuan Wang, Jianmin Lu   +3 more
openalex   +2 more sources