Results 201 to 210 of about 758,578 (355)

The T393C Polymorphism of the Gαs Gene (GNAS1) Is a Novel Prognostic Marker in Bladder Cancer [PDF]

, 2005
Ulrich H. Frey, A. Eisenhardt, G. Lümmen, H. Rübben, Karl-Heinz Jöckel, Kurt Werner Schmid, Winfried Siffert   +6 more
openalex   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Association Between <i>VKORC1</i> Gene Polymorphisms and Osteopenia and Osteoporosis: A Systematic Review and Meta-Analysis. [PDF]

Medicina (Kaunas)
Vesa ŞC, Ichim VM, Iluț S, Miglietta S, Lupu M, Coada CA, Macarie AE, Chiroban O, Buzoianu AD, Sabin O.   +9 more
europepmc   +1 more source

Polymorphisms and Haplotypes of the <i>CD209L</i> Gene and Their Association with the Clinical Courses of HIV-Positive Japanese Patients

, 2002
Noriko Kobayashi, Hitomi Taguchi-Nakamura, Mieko Goto, Tetsuya Nakamura, Koichiro Nakamura, Wataru Sugiura, Aikichi Iwamoto, Yoshihiro Kitamura   +7 more
openalex   +2 more sources

Influences of Chymase and Angiotensin I-Converting Enzyme Gene Polymorphisms on Gastric Cancer Risks in Japan [PDF]

, 2006
Mitsushige Sugimoto, Takahisa Furuta, Naohito Shirai, Mutsuhiro Ikuma, Haruhiko Sugimura, Akira Hishida   +5 more
openalex   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Association between CYP2C19 gene polymorphisms and Helicobacter pylori infection in Hainan region. [PDF]

BMC Infect Dis
Huang S, Zhang D, Li D, Chen C, Zeng F, Chen S, Chen R, Zhang X, Bai F.   +8 more
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Managing Refractory Hypertension: A Case Study Exploring the Influence of ACE and ACTN3 Gene Polymorphisms. [PDF]

Pharmgenomics Pers Med
Gasser B, Dössegger A, Flück M.
europepmc   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source