Results 31 to 40 of about 2,842,251 (254)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Genetic Resources, 2020 In Rwanda, the most prevalent livestock farming activity carried out to improve livelihoods in rural areas is poultry farming. The most common bird species raised for egg and meat production is indigenous chicken (IC).
Richard Habimana +9 more
doaj +1 more source
Parasites & Vectors, 2019 Background Ticks participate as arthropod vectors in the transmission of pathogenic microorganisms to humans. Several tick-borne infections have reemerged, along with newly described agents of unexplored pathogenicity.
Annika Brinkmann +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Acta Agronómica, 2007 <span style="font-size: 10pt; font-family: Verdana">In this study, 180 genotypes of cultivated <em>Phaseolus vulgaris </em>from the Caribbean were evaluated with the phaseolin marker.
Hidalgo Rigoberto +2 more
doaj
Characterization of the naive murine antibody repertoire using unamplified high-throughput sequencing. [PDF]
PLoS ONE, 2018 Antibody specificity and diversity are generated through the enzymatic splicing of genomic gene segments within each B cell. Antibodies are heterodimers of heavy- and light-chains encoded on separate loci.
Trisha A Rettig +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Veterinaria Italiana, 2019 An outbreak of Peste des petits ruminants (PPR) occurred in the Antalya Province in Turkey during October 2015. The Antalya Province has suitable habitats for vectors. There is no information available on the role of Culicoides spp.
Murat Şevik, Mustafa Emin OZ
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Gene flow within and between catchments in the threatened riparian plant Myricaria germanica. [PDF]
PLoS ONE, 2014 One of the major distinctions of riparian habitats is their linearity. In linear habitats, gene flow is predicted to follow a one-dimensional stepping stone model, characterized by bidirectional gene flow between neighboring populations. Here, we studied
Silke Werth, Christoph Scheidegger
doaj +1 more source