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Mapping and predicting gene–enhancer interactions [PDF]

Nature Genetics, 2019
A new study presents a powerful experimental approach, CRISPRi-FlowFISH, for mapping regulatory interactions, and uses it to characterize thousands of putative enhancer–gene pairs. The results suggest that most current approaches for predicting enhancer–gene interactions perform poorly, but a simple mathematical model combining distance with enhancer ...
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Gene function prediction with knowledge from gene ontology

International Journal of Data Mining and Bioinformatics, 2015
Gene function prediction is an important problem in bioinformatics. Due to the inherent noise existing in the gene expression data, the attempt to improve the prediction accuracy resorting to new classification techniques is limited. With the emergence of Gene Ontology (GO), extra knowledge about the gene products can be extracted from GO and ...
Ying Shen, Lin Zhang
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Prediction of Plant miRNA Genes

2009
This chapter presents procedures for the computational identification of plant miRNA genes. In the first procedure, homologs of known miRNAs are identified in a database of genomic or cDNA sequence. In the second procedure, previously unidentified miRNA families are predicted through the analysis of secondary structure, evolutionary conservation, and ...
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GeMoMa: Homology-Based Gene Prediction Utilizing Intron Position Conservation and RNA-seq Data.

Methods in molecular biology, 2019
J. Keilwagen, F. Hartung, Jan Grau
semanticscholar   +1 more source

Genes, diabetes and cardiovascular risk prediction

Nature Reviews Endocrinology, 2009
A region of chromosome 9p21 is linked to an increased risk of coronary artery disease in the general population. Variants of the same allele might also affect risk of cardiovascular disease in patients with type 2 diabetes mellitus, according to a new study.
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The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies

Ca-A Cancer Journal for Clinicians, 2022
Michal Kuten-shorrer, Noam Yarom, Sharon Elad   +2 more
exaly  

No gene to predict the future?

European Journal of Human Genetics, 2022
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Highly accurate protein structure prediction with AlphaFold

Nature, 2021
Demis Hassabis, Simon A A Kohl, Alexander Pritzel   +2 more
exaly  

Gene Prediction: Methods and Protocols

Methods in Molecular Biology, 2019
Martin Kollmar
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Genomic‐derived radiation dosage improves prediction of outcomes

Ca-A Cancer Journal for Clinicians, 2022
exaly