Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection [PDF]
, 2008 During acute human immunodeficiency virus type 1 (HIV-1) infection, early host cellular immune responses drive viral evolution. The rates and extent of these mutations, however, remain incompletely characterized.
Carrington, M. +20 more
core
Stability of gag-ca gene of Jembrana Virus in pcDNA-ca recombinant plasmid vector in Escherichia coli DH5α which has been stored for eight years [PDF]
, 2015 The aim of this study was to determine the stability of gag-ca gene in a pcDNA-ca recombinant plasmid vector in Escherichia coli DH5α which has been stored for eight years using Polymerase Chain Reaction method (PCR).
Puspitasari, Endah +4 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun +7 more
wiley +1 more source
An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula +8 more
wiley +1 more source
Translation Efficiency of the Human T-Cell Leukemia Virus (HTLV-2) gag Gene Modulates the Frequency of Ribosomal Frameshifting [PDF]
, 1995 The regulation of ribosomal frameshifting during translation of the polycistronic mRNA of human T-cell leukemia virus (HTLV) was studied in a cell-free system.
Mador, Nurith +4 more
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Advanced NanoBiomed Research, EarlyView.Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley +1 more source
Recombinant BCG expressing HIV-1 C GAG : selection of the vaccine gene and construction and evaluation as a vaccine candidate [PDF]
, 2005 Includes bibliographical ...
Thomas, Robin
core +1 more source
Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs
The Anatomical Record, EarlyView.Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy +3 more
wiley +1 more source
Heavy chain gene analysis of Gag-only VLP binding antibodies.
, 2015 Heavy chain gene analysis of Gag-only VLP binding antibodies.
Gary Landucci (53376) +9 more
core +1 more source
Domesticated retroviral GAG gene in Drosophila: New functions for an old gene [PDF]
, 2014 The domestication of foreign genes is a powerful mechanism for new gene formation and genome evolution. It is known that domesticated retroviral gag genes in mammals not only take part in protecting against viral infection but also control cell division,
Kim, A.I. +3 more
core +1 more source