Results 191 to 200 of about 5,314,306 (291)

Rapid Translation of the Early Coding Region Promotes Premature Transcription Termination, Reducing Protein Expression in Escherichia coli

Molecular Microbiology, EarlyView.
A run of consecutive fast‐translated codons (right) within the first 30 codons of lacZ (top) causes loss of the downstream transcript at positions coinciding with previously mapped intragenic Rho‐dependent termination sites (middle), and a corresponding loss of β‐galactosidase activity (bottom).
Steen Pedersen, Alberte Honoré Jepsen, Bertil Gummesson, Namiko Mitarai, Kim Sneppen, Sine Lo Svenningsen   +5 more
wiley   +1 more source

Engineering Viral Surface Antigens to Improve Display on Virus-like Particle (VLP) Vaccine Prototypes. [PDF]

BioTech (Basel)
Pißarreck M, Katsoutas K, Stitz J.
europepmc   +1 more source

The host range paradox of Meloidogyne incognita: a physiological and transcriptomic analysis of nine susceptible interactions across six plant orders

New Phytologist, EarlyView.
Phylogenetic distance of host does not explain phenotypic differences of Meloidogyne incognita parasitism at 25 dpi. Summary The plant–parasitic nematode Meloidogyne incognita is the pathogen with the broadest host range among all known biotrophic interactions.
Victor Hugo Moura de Souza, Clement Pellegrin, Vincent C. T. Hanlon, Chongjing Xia, Olaf P. Kranse, Unnati Sonawala, Priya Desikan, Beatrice Senatori, Lucie Bolelli, Etienne G. J. Danchin, Lida Derevnina, Sebastian Eves‐van den Akker   +11 more
wiley   +1 more source

The Disruption of the HIV-1 Gag Start Codon via Editing Using MmCas12m-Dual Base Editor-Loaded Virus-like Particles. [PDF]

Curr Issues Mol Biol
Aliev T, Imatdinov A, Prudnikova E, Taranov O, Emtsova K, Imatdinov I, Agafonov A.   +6 more
europepmc   +1 more source

Gene Allen Oral History (part 1)

Gene Allen, Art Director of "My Fair Lady", "A Star is Born", and "Les Girls".

core  

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to investigate gene mutations in ameloblastic carcinoma (AC) including BRAF, KRAS, and PIK3CA, along with associated protein expressions of BRAF V600E, p‐ERK1/2, and p‐mTOR, which represent activation of MAPK/ERK and PI3K/mTOR pathways, respectively.
Puangwan Lapthanasupkul, Jintana Pankam, Siribang‐on Piboonniyom Khovidhunkit, Prapapun Seneetuntigul, Nakarin Kitkumthorn   +4 more
wiley   +1 more source

Combination treatment with synthetic gRNA/Cas12a and gRNA/Cas9 ribonucleoproteins disrupts HIV replication and expression. [PDF]

iScience
Banik P, Wang L, Schank M, Pyburn JS, Hill AC, Zhang Y, Zhao J, Orfield HK, Leshaodo TO, Lightner JW, Wu XY, Ning S, El Gazzar M, Moorman JP, Yao ZQ.   +14 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

TCR γδ cell-specific STAT5 gain of function induces a druggable chronic human immune dysregulation. [PDF]

J Hum Immun
Meyer BJ, Loureiro JP, Nosi V, Hupfer R, Ghosh A, Poletti F, Jauch A, Hirsiger J, Berkemeier C, Heijnen I, Dirks J, Alborelli I, Menter T, Tzankov A, Hess C, Navarini AA, Berger CT, Mori L, De Libero G, Recher M.   +19 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source