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Inferring latent gene regulatory network kinetics
Statistical Applications in Genetics and Molecular Biology, 2013Regulatory networks consist of genes encoding transcription factors (TFs) and the genes they activate or repress. Various types of systems of ordinary differential equations (ODE) have been proposed to model these networks, ranging from linear to Michaelis-Menten approaches.
González, Javier +2 more
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Switching Gene Regulatory Networks
2015A fundamental question in biology is how cells change into specific cell types with unique roles throughout development. This process can be viewed as a program prescribing the system dynamics, governed by a network of genetic interactions. Recent experimental evidence suggests that these networks are not fixed but rather change their topology as cells
Yoli Shavit +5 more
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Evolving gene regulatory networks
Biosystems, 2009Jin, Yaochu, Hallinan, Jennifer
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly