Results 31 to 40 of about 276 (89)

CDX2 dose-dependently influences the gene regulatory network underlying human extraembryonic mesoderm development. [PDF]

Biol Open
Bulger EA, McDevitt TC, Bruneau BG.
europepmc   +1 more source

Brahma safeguards canalization of cardiac mesoderm differentiation. [PDF]

Nature, 2022
Hota SK, Rao KS, Blair AP, Khalilimeybodi A, Hu KM, Thomas R, So K, Kameswaran V, Xu J, Polacco BJ, Desai RV, Chatterjee N, Hsu A, Muncie JM, Blotnick AM, Winchester SAB, Weinberger LS, Hüttenhain R, Kathiriya IS, Krogan NJ, Saucerman JJ, Bruneau BG.   +21 more
europepmc   +1 more source

Characterizing and controlling CRISPR repair outcomes in nondividing human cells. [PDF]

Nat Commun
Ramadoss GN, Namaganda SJ, Kumar MM, Hamilton JR, Sharma R, Chow KG, Workley LA, Macklin BL, Sun M, Ha AS, Liu JC, Fellmann C, Watry HL, Dierks PH, Bose RS, Jin J, Perez BS, Sandoval Espinoza CR, Matia MP, Lu SH, Judge LM, Shy BR, Nussenzweig A, Adamson B, Murthy N, Doudna JA, Kampmann M, Conklin BR.   +27 more
europepmc   +1 more source

Evaluation of CRISPR/Cas9 exon-skipping vector for choroideremia using human induced pluripotent stem cell-derived RPE. [PDF]

J Gene Med, 2023
Iwagawa T, Masumoto H, Tabuchi H, Tani K, Conklin BR, Watanabe S.   +5 more
europepmc   +1 more source

Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells. [PDF]

Dev Cell, 2023
Vasic I, Libby ARG, Maslan A, Bulger EA, Zalazar D, Krakora Compagno MZ, Streets A, Tomoda K, Yamanaka S, McDevitt TC.   +9 more
europepmc   +1 more source

Modeling <i>SMAD2</i> Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis. [PDF]

J Am Heart Assoc
Ward T, Morton SU, Venturini G, Tai W, Jang MY, Gorham J, Delaughter D, Wasson LK, Khazal Z, Homsy J, Gelb BD, Chung WK, Bruneau BG, Brueckner M, Tristani-Firouzi M, DePalma SR, Seidman C, Seidman JG.   +17 more
europepmc   +1 more source

SARS-CoV-2 can infect human embryos. [PDF]

Sci Rep, 2022
Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, Zouves CG, Greene WC, Viotti M.   +12 more
europepmc   +1 more source

Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis. [PDF]

Bioinform Adv, 2022
Blair AP, Hu RK, Farah EN, Chi NC, Pollard KS, Przytycki PF, Kathiriya IS, Bruneau BG.   +7 more
europepmc   +1 more source

Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins. [PDF]

Nat Commun
Xu D, Besselink S, Ramadoss GN, Dierks PH, Lubin JP, Pattali RK, Brim JI, Christenson AE, Colias PJ, Ornelas IJ, Nguyen CD, Chasins SE, Conklin BR, Nuñez JK.   +13 more
europepmc   +1 more source

Transcription factor protein interactomes reveal genetic determinants in heart disease. [PDF]

Cell, 2022
Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D.   +27 more
europepmc   +1 more source