Results 211 to 220 of about 631,661 (355)

Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2

, 2004
Loris De Cecco, Luigi Marchionni, Manuela Gariboldi, James F. Reid, Maria Stefania Lagonigro, Stefano Caramuta, Cristina Ferrario, Erica Bussani, Delia Mezzanzanica, Fabio Turatti, Domenico Delia, Maria Grazia Daidone, Maria Oggionni, Norma Bertuletti, Antonino Ditto, Francesco Raspagliesi, Silvana Pilotti, Marco A. Pierotti, Silvana Canevari, Claudio Schneider   +19 more
openalex   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Identification of a 3-gene signature predicting 28-day mortality for sepsis. [PDF]

Medicine (Baltimore)
Zeng Y, Liao Y, Wang Y, Peng S.
europepmc   +1 more source

Signatures of Selection and Gene Conversion Associated with Human Color Vision Variation

, 2004
Brian C. Verrelli, Sarah A. Tishkoff
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Expressed Sequence Tag-Linked Microsatellites as a Source of Gene-Associated Polymorphisms for Detecting Signatures of Divergent Selection in Atlantic Salmon (Salmo salar L.) [PDF]

, 2005
Anti Vasemägi, Jan Nilsson, Craig R. Primmer   +2 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

401-Gene Signature of Myocardial Dysfunction in Human Heart Failure: A Transcriptomic Analysis. [PDF]

Cureus
Estes-Schmalzl KJ, Marcano-Reik AJ, Lefebvre KM.   +2 more
europepmc   +1 more source

Liver Gene Expression Signature of Mild Fibrosis in Patients With Chronic Hepatitis C [PDF]

, 2005
Tarik Asselah, Ivan Bièche, Ingrid Laurendeau, Valérie Paradis, Dominique Vidaud, Claude Degott, Michelle Martinot, Pierre Bédossa, Dominique Valla, Michel Vidaud, Patrick Marcellin   +10 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source