Results 211 to 220 of about 11,459,182 (339)

Development of new virus vectors for gene therapy.

, 1994
Takashi Shimada
openalex   +2 more sources

Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. [PDF]

, 1995
Alain R. Thierry, Yanto Lunardi-Iskandar, Joseph Bryant, P Rabinovich, R C Gallo, L C Mahan   +5 more
openalex   +1 more source

Gene Therapy in Patients with Transfusion‐Dependent β‐Thalassemia

New England Journal of Medicine, 2018
A. Thompson, M. Walters, J. Kwiatkowski, J. Rasko, J. Ribeil, S. Hongeng, E. Magrin, G. Schiller, E. Payen, M. Semeraro, D. Moshous, F. Lefrère, H. Puy, P. Bourget, A. Magnani, L. Caccavelli, J. Diana, F. Suarez, F. Monpoux, V. Brousse, C. Poirot, C. Brouzes, J. Meritet, C. Pondarré, Y. Beuzard, S. Chrétien, T. Lefèbvre, D. Teachey, U. Anurathapan, P. Ho, C. von Kalle, M. Kletzel, E. Vichinsky, S. Soni, G. Veres, O. Nègre, R. W. Ross, D. Davidson, Alexandria Petrusich, L. Sandler, M. Asmal, O. Hermine, M. de Montalembert, S. Hacein-Bey-Abina, S. Blanche, P. Leboulch, M. Cavazzana   +46 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Unlocking the potential: advancements and applications of gene therapy in severe disorders. [PDF]

Ann Med
Ingle RG, M Elossaily G, Ansari MN, Makhijani S.   +3 more
europepmc   +1 more source

Towards Somatic Gene Therapy of Hemophilia B

, 1992
Yukinori Kurachi
openalex   +2 more sources

Transferrin-Liposome-Mediated Systemic p53 Gene Therapy in Combination with Radiation Results in Regression of Human Head and Neck Cancer Xenografts [PDF]

, 1999
Liang Xu, Kathleen F. Pirollo, Wenhua Tang, Antonina Rait, Esther H. Chang   +4 more
openalex   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Tumor-specific AAV delivery of interleukin-12 enhances antitumor immunity and safety in ovarian cancer xenograft mouse model

Molecular Therapy: Oncology
Interleukin-12 (IL-12) is a promising pro-inflammatory cytokine for cancer immunotherapy, but its toxicity and short half-life in serum limit its clinical application.
Chuyuan Chen, Yongji Jiang, Chuan Feng, Qingyun Zhou, Xingrong Luo, Lili Cai, Lei Zhao   +6 more
doaj  

The promise of gene therapy in common types of dementia. [PDF]

Bioimpacts
Ghobadi M, Heidari MF, Farhadi A, Shakerimoghaddam A, Ghorbani M, Hami Z, Ehtesham N, Behroozi J.   +7 more
europepmc   +1 more source