Results 271 to 280 of about 2,093,614 (359)

State-of-the-art gene therapy for inherited retinal disorders

O.I. Orenburkina, A.E. Babushkin
openalex   +1 more source

Potential for promoting recurrent laryngeal nerve regeneration by remote delivery of viral gene therapy

, 2011
Adam D. Rubin, Norman D. Hogikyan, Alex Oh, Eva L. Feldman   +3 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Principles of gene therapy of the inner ear. [PDF]

Curr Opin Otolaryngol Head Neck Surg
Lin JS, Shibata SB.
europepmc   +1 more source

Cellular transplantation and gene therapy. [PDF]

, 1993
Ildstad, ST, Ricordi, C, Starzl, TE
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Reality bites: allocating gene therapy for hemoglobinopathies. [PDF]

Blood Adv
Tubman VN, Fasipe TA.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Hybrid Nanocarriers for Cancer Therapy: Advancements in Co-Delivery of Gene Therapy and Immunotherapy. [PDF]

Int J Mol Sci
Berikkhanova K, Inuwa I, Jibo AG, Berikkhanov N, Bikhanov N, Sultan Y, Omarbekov A.   +6 more
europepmc   +1 more source

Association of Warfarin Therapy with APOE and VKORC1 Genes Polymorphism in Iranian Population.

, 2017
Sajad Rafiee, Masoumeh Rajabibazl, Reza Meshkani, Azam Daraei, Mehryar Zargari, Fahimeh Sharafeddin, Zahra Fazeli, Attabak Toffani Milani, Maryam Taherkhani   +8 more
openalex   +1 more source