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Topological data analysis captures horizontal gene transfer in antimicrobial resistance gene families among clinically relevant bacteria [PDF]

open access: yesFrontiers in Microbiology
Antibiotic resistance, projected to cause 10 million deaths annually by 2050, remains a critical health threat. Hospitals drive multidrug resistance via horizontal gene transfer.
Shaday Guerrero-Flores   +6 more
doaj   +2 more sources

Horizontal gene transfer of molecular weapons can reshape bacterial competition. [PDF]

open access: yesPLoS Biology
Bacteria commonly use molecular weaponry to kill or inhibit competitors. Genes encoding many weapons and their associated immunity mechanisms can be transmitted horizontally.
Elisa T Granato   +5 more
doaj   +2 more sources

Double-stranded DNA viruses may serve as vectors for horizontal transfer of intron-generating transposons [PDF]

open access: yesMobile DNA
Specialized transposable elements capable of generating introns, termed introners, are one of the major drivers of intron gain in eukaryotes. Horizontal transfer of transposable elements (HTT) is thought to play an important role in shaping introner ...
Landen Gozashti, Russell Corbett-Detig
doaj   +2 more sources

Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones

open access: yesNature Communications, 2022
In this work, the authors determine the crystal structure of a ProQ/FinO RNA chaperone bound to its RNA target. This provides insight into how this family of bacterial proteins recognize transcriptional terminator structures.
Hyeong Jin Kim   +16 more
doaj   +1 more source

Staphylococcus equorum plasmid pKS1030-3 encodes auxiliary biofilm formation and trans-acting gene mobilization systems

open access: yesScientific Reports, 2023
The foodborne bacterium Staphylococcus equorum strain KS1030 harbours plasmid pSELNU1, which encodes a lincomycin resistance gene. pSELNU1 undergoes horizontal transfer between bacterial strains, thus spreading antibiotic resistance.
Sojeong Heo   +8 more
doaj   +1 more source

The Routes of Emergence of Life from LUCA during the RNA and Viral World: A Conspectus

open access: yesLife, 2015
How did life emerge on Earth? The aim of the Network of Researchers on Horizontal Gene Transfer and the Last Universal Cellular Ancestor (NoR HGT & LUCA) is to understand how the genetics of LUCAs were reorganised prior to the advent of the three ...
Sohan Jheeta
doaj   +1 more source

Examining Ancient Inter-domain Horizontal Gene Transfer

open access: yesEvolutionary Bioinformatics, 2008
Details of the genomic changes that occurred in the ancestors of Eukarya, Archaea and Bacteria are elusive. Ancient interdomain horizontal gene transfer (IDHGT) amongst the ancestors of these three domains has been difficult to detect and analyze because
Francisca C. Almeida   +3 more
doaj   +2 more sources

Adsorption and Oxidation of Aromatic Amines on Metal(II) Hexacyanocobaltate(III) Complexes: Implication for Oligomerization of Exotic Aromatic Compounds

open access: yesInorganics, 2017
Based on the hypothesis on the presence of double metal cyanides in the primordial oceans, a series of nano-sized metal(II) hexacyanocobaltate(III) (MHCCo) with the general formula: M3[Co(CN)6]2•xH2O (where M = Zn, Fe, Ni and Mn) has been synthesized ...
Rachana Sharma   +3 more
doaj   +1 more source

Amino acid sequence associated with bacteriophage recombination site helps to reveal genes potentially acquired through horizontal gene transfer

open access: yesBMC Bioinformatics, 2020
Background Horizontal gene transfer, i.e. the acquisition of genetic material from nonparent organism, is considered an important force driving species evolution. Many cases of horizontal gene transfer from prokaryotes to eukaryotes have been registered,
Maria A. Daugavet   +2 more
doaj   +1 more source

Shaping the Landscape of Eukaryotic Gene Expression: Horizontal Gene Transfer

open access: yesAsian Journal of Medical Sciences, 2021
Horizontal gene transfer (HGT) in prokaryotes refers to the movement of genes and genetic information between two organisms. This usually results in the spread of antibiotic resistance genes among bacteria. Vertical gene transfer(VGT), on the other hand,
Ruby Dhar   +2 more
doaj   +1 more source

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