Results 111 to 120 of about 287,974 (300)

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post–transfer refinement [PDF]

, 2015
When microbes acquire new abilities through horizontal gene transfer, the genes and pathways must function under conditions with which they did not coevolve.
Bringel, Françoise, Camargo Neves, Aline A, Marx, Christopher J, Michener, Joshua K, Vuilleumier, Stéphane   +4 more
core   +1 more source

Horizontal gene transfer in human pathogens [PDF]

Critical Reviews in Microbiology, 2013
Horizontal gene transfer has a tremendous impact on the genome plasticity, adaptation and evolution of bacteria. Horizontally transferred mobile genetic elements are involved in the dissemination of antibiotic resistance and virulence genes, thus contributing to the emergence of novel "superbugs".
openaire   +3 more sources

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Ancient horizontal gene transfer and the last common ancestors [PDF]

, 2015
Background The genomic history of prokaryotic organismal lineages is marked by extensive horizontal gene transfer (HGT) between groups of organisms at all taxonomic levels. These HGT events have played an essential role in the origin and distribution of
A Barzel, A Burt, A Hua-Van, A Sauerwald, A Stoltzfus, AM Barbaglia, B Boussau, B Reisinger, C Darwin, Cheryl P Andam, CP Andam, CP Andam, CR Woese, CR Woese, D Darriba, D Williams, DA Benson, DH Rothman, EGJ Danchin, EV Koonin, EV Koonin, EV Koonin, G Borrel, G Borrel, G Eriani, G Srinivasan, GJ Szöllosi, GM Nagel, GP Fournier, GP Fournier, GP Fournier, Gregory P Fournier, H Grosjean, J Peretó, J Thomas, JA Krzycki, JA Krzycki, JAG Ranea, JL Siefert, JM Kavran, Johann Peter Gogarten, JP Gogarten, K Swithers, K Vetsigian, L Olendzenski, L Ribas de Pouplana, L Ribas de Pouplana, L Sinzelle, LS Frost, M Ibba, M Khomyakova, M Syvanen, M Wu, MH Mazauric, MV Omelchenko, N Lartillot, N Nameki, O Penn, O Zhaxybayeva, P Kück, P Kück, P O’Donoghue, P O’Donoghue, P Schimmel, R Dawkins, R Jain, RC Edgar, S Bilokapic, S Gould, S Guindon, S Herring, S Herring, S Morris, S Osawa, SQ Le, T Tuller, TJ Treangen, VV Kapitonov, WM Fitch, Y Diaz-Lazcoz, Y Zhang, YI Wolf, Z-P Fang   +82 more
core   +2 more sources

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

Advanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte, Marta Serra, Simon Kahlenberg, Guruprakash Subbiahdoss, Erik Reimhult, Dominik Egger, Cornelia Kasper   +6 more
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Measuring degradation of transgenic DNA and screening for horizontal gene transfer from GMO-plant material during composting [PDF]

, 2004
The experiments show that composting of GM plant residues greatly increases the rate of degradation of transgenic DNA compared to the rate for plant residues left in the soil.
Magid, Jakob, Moeller, Jacob, Rasmussen, Lasse Dam   +2 more
core  

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Vertical and horizontal transfer of genes in lichens [PDF]

, 2013
Mnoge se pojave u evoluciji živog svijeta mogu objasniti simbiozom. Simbioza kao pojava u živom svijetu dala je mnoge prednosti samim organizmima koji u nju stupaju, ali je i neposredno ubrzala evoluciju živog svijeta.
Tunjić, Monika
core   +2 more sources