Results 241 to 250 of about 287,974 (300)

Green‐to‐red spectral labeling: A novel polysynaptic retrograde tracing strategy in the marker footprint mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To compensate for the fluorescence loss in rabies virus–derived neuronal tracing tools caused by non‐cytolytic immune clearance (NCLIC) in retrograde tracing, we developed a novel green‐to‐red spectral labeling (GTR) strategy based on the NCLIC phenomenon and developed a novel marker footprints mouse to support the strategy.
Yige Song   +4 more
wiley   +1 more source

Physiology, Heavy Metal Resistance, and Genome Analysis of Two <i>Cupriavidus gilardii</i> Strains Isolated from the Naica Mine (Mexico). [PDF]

open access: yesMicroorganisms
González-Sánchez A   +6 more
europepmc   +1 more source

Long‐term immunosuppression of rabbits through oral tacrolimus administration

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Oral gavage of rabbits with 1.5 mg/kg/d of tacrolimus allows for an efficient long‐term (1 year) immunosuppression with minimal side effects and no loss of animals. lmmunosuppressed rabbits are a convenient animal model to investigate the long‐term efficacy of human allografts in vivo.
Alexane Thibodeau   +4 more
wiley   +1 more source

Comparative analysis of two newly established Cre rat lines, NeuN‐Cre and Thy1‐Cre, for neurological research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li   +15 more
wiley   +1 more source

Metagenomic analysis of human, animal, and environmental samples identifies potential emerging pathogens, profiles antibiotic resistance genes, and reveals horizontal gene transfer dynamics. [PDF]

open access: yesSci Rep
Napit R   +12 more
europepmc   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

open access: yesAdvanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael   +10 more
wiley   +1 more source

Design and Application of Piezoelectric Conductive Smart Scaffold for Noninvasive Neural Tissue Regeneration via Custom‐Made In Vitro Mechano‐Stimulator

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic illustration showing the design of the developed invitro mechano stimulator (IMS) and the electrospun nanofiber‐based piezoelectric and conductive nerve conduit (PCNC) that can self‐generate electrical stimulations analogous to neural tissues. IMS provided vital electrical cues for the neural cells to attach, align and proliferate on the PCNC
Afeesh Rajan Unnithan   +5 more
wiley   +1 more source

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