Results 101 to 110 of about 898,857 (281)
Advanced Healthcare Materials, EarlyView.This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans +11 more
wiley +1 more source
iGTP: A software package for large-scale gene tree parsimony analysis
BMC Bioinformatics, 2010 Background The ever-increasing wealth of genomic sequence information provides an unprecedented opportunity for large-scale phylogenetic analysis. However, species phylogeny inference is obfuscated by incongruence among gene trees due to evolutionary ...
Fernández-Baca David +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni +15 more
wiley +1 more source
Biologically feasible gene trees, reconciliation maps and informative triples
Algorithms for Molecular Biology, 2017 Background The history of gene families—which are equivalent to event-labeled gene trees—can be reconstructed from empirically estimated evolutionary event-relations containing pairs of orthologous, paralogous or xenologous genes.
Marc Hellmuth
doaj +1 more source
Accounting for Gene Tree Uncertainties Improves Gene Trees and Reconciliation Inference [PDF]
, 2012 We propose a reconciliation heuristic accounting for gene duplications, losses and horizontal transfers that specifically takes into account the uncertainties in the gene tree. Rearrangements are tried for gene tree edges that are weakly supported, and are accepted whenever they improve the reconciliation cost. We prove useful properties on the dynamic
Thi Hau Nguyen +5 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
Phylogenomic comparative methods: Accurate evolutionary inferences in the presence of gene tree discordance. [PDF]
Proc Natl Acad Sci U S A, 2023 Hibbins MS, Breithaupt LC, Hahn MW.
europepmc +1 more source
Two‐Photon 3D Printing of Functional Microstructures Inside Living Cells
Advanced Materials, EarlyView.This study demonstrates 3D printing inside living cells by using two‐photon photo‐lithography. A bio‐compatible photoresist is injected into cells and selectively polymerized with a femtosecond laser, creating custom‐shaped intracellular structures with submicron resolution.
Maruša Mur +4 more
wiley +1 more source
Editorial: Phylogenomic discordance in plant systematics
Frontiers in Plant Science, 2023 Stefan Wanke, Stefan Wanke, Susann Wicke
doaj +1 more source