Results 101 to 110 of about 35,832,141 (372)
European Journal of General Practice, 2017 Background: Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in residential long-term care facilities experiencing inappropriate medication use.
Hannelore Storms +3 more
doaj +1 more source
Вестник Мининского университета, 2017 Introduction: The approaches to understanding the crisis of culture in the context of Russian philosophical thought at the turn of the 19th-20th centuries are considered in this article.
A. I. Simonov
doaj +1 more source
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
FEBS Letters, EarlyView.The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran +6 more
wiley +1 more source
AIECE general report; report submitted at the general meeting of 5-6 November 2009 [PDF]
The worst part of the financial crisis is behind us. Nevertheless, the fall in global output in 2009 will be the largest of the post-war period. As a result, unemployment and government deficits are rising steeply this year, while inflation will be very ...
Douwe Kingma +3 more
core
Turbulent General Magnetic Reconnection
, 2014 Plasma flows with an MHD-like turbulent inertial range, such as the solar wind, require a generalization of General Magnetic Reconnection (GMR) theory. We introduce the slip-velocity source vector, which gives the rate of development of slip velocity per
Eyink, Gregory L.
core +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Continuing Medical Education Program: a credit system evaluation [PDF]
Einstein (São Paulo), 2008 Objectives: To analyze the Continuing Medical Education (CME)program developed at the Hospital Israelita Albert Einstein, formallyinitiated in 2002, carried out in six successive 12-month cyclesand focused on participating physicians, as to compliance ...
Claudio Schvartsman +5 more
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