Results 111 to 120 of about 9,713,281 (274)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Формування предметного поля метафізичних категорій у просторі філософських ідей Пізньої схоластики / The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastic

open access: yesАктуальні питання суспільних наук та історії медицини, 2014
Skrytska Natalya. The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastics. The article considers the nature of such metaphysical concepts as essence, being, God, substance, logical quantifier ...
Скрицька Наталія
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Indice General

open access: yesRevista Técnica de la Facultad de Ingeniería, 2019
Indice Vol 42 ...
Valentina Millano
doaj  

Democratising the design and delivery of large-scale randomised, controlled clinical trials in primary care: A personal view

open access: yesEuropean Journal of General Practice
Background Rapid identification of effective treatments for use in the community during a pandemic is vital for the well-being of individuals and the sustainability of healthcare systems and society.
Christopher C. Butler
doaj   +1 more source

The Practice of Using the Discriminant Analysis of the Efficiency of Processes of Functioning of Agricultural Enterprises on the Basis of Indicators of the Constituent Parts of Performance [PDF]

open access: yesBìznes Inform, 2018
The article considers the practice of using the method of discriminant analysis to study effectiveness of the processes of functioning of enterprises on the basis of indicators of the constituent parts of performance on the example of specific ...
Burennikova Nataliia V., Marchuk Lina M.
doaj  

Quasitoric representation of generalized braids [PDF]

open access: yesarXiv
In this paper, we define generalized braid theories in alignment with the language of Fenn and Bartholomew for knot theories, and compute a generating set for the pure generalized braid theories. Using this, we prove that every oriented normal generalized knot is the closure of a quasitoric normal generalized braid.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

A representation theorem for generators of BSDEs with general growth generators in $y$ and its applications [PDF]

open access: yesarXiv, 2017
In this paper we first prove a general representation theorem for generators of backward stochastic differential equations (BSDEs for short) by utilizing a localization method involved with stopping time tools and approximation techniques, where the generators only need to satisfy a weak monotonicity condition and a general growth condition in $y$ and ...
arxiv  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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