Results 81 to 90 of about 86,776 (278)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Остеопороз и остеопатии, 2009 It is spent prospective 15 years research on studying combined pathologies (the atherosclerotic cardiovascular diseases and osteoporosis) and the general risk factors of these diseases in women at transition from reproductive in postmenopausal period. It
I A Skripnikova, R G Oganov
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
AN EFFECTIVE RECOMMENDATIONS BY DIFFUSION ALGORITHM FOR WEB GRAPH MINING [PDF]
ICTACT Journal on Soft Computing, 2013 The information on the World Wide Web grows in an explosive rate. Societies are relying more on the Web for their miscellaneous needs of information. Recommendation systems are active information filtering systems that attempt to present the information ...
S. Vasukipriya, T. Vijaya Kumar
doaj
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
How important is a bike park visit for the overall tourist destination experience?
Cogent Social Sciences, 2019 Tourism has become a highly competitive sector, forcing destinations to reinvent and constantly enhance extraordinary experiences in accordance with their miscellaneous destination characteristics, whilst considering mountain biking as a growing ...
Philipp Schlemmer +4 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Journal of Tropical Forestry and Environment, 2014 An investigation was carried out on selected 20 timber species of Sri Lanka to study different wood properties, i.e., wood density, modulus of rapture, modulus of elasticity, compression parallel to grain, shrinkage/movement, workability (sawing ...
ND Ruwanpathirana
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The spectrum of non- neoplastic skin lesions in Ibadan, Nigeria: a histopathologic study
The Pan African Medical Journal, 2016 INTRODUCTIO: non-neoplastic skin lesions constitute the majority of skin diseases. There is a paucity of histopathology studies of non-neoplastic skin diseases in Nigeria and the West Africa sub-region in general.
Gabriel Olabiyi Ogun +1 more
doaj +1 more source