Results 101 to 110 of about 604,229 (308)

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner, Ellen M. Cody, Prasad Devarajan, Bin Huang, Chen Chen, Dominic Sinibaldi, Madhu Ramaswamy, Jacob Knagenhjelm, Frederick Jones, Philip Z. Brohawn, Raj Tummala, Catharina Lindholm, Wendy I. White   +12 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

BMC Pharmacology and Toxicology, 2019
Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects.
Megan McGrath, Alissa Hofmann, Douglas E. Raines   +2 more
doaj   +1 more source

Myocardial Infarction After General Anesthesia [PDF]

, 1972
Few statistics are available about the incidence of primary or recurrent myocardial infarction after anesthesia. Mortality rates and their relation to age and sex, and to type and duration of anesthesia in existing reports, are based on a relatively ...
Giuliani, Emilio R., Moffitt, Emerson A., Tarhan, Sait, Taylor, William F.   +3 more
core   +2 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Morphine Use in Cancer Surgery [PDF]

, 2011
Morphine is the core of perioperative pain management. However, when it comes to cancer surgery the possibility that this drug might affect tumor recurrence and metastasis has raised concerns.
Banafsheh Afsharimani, Peter J. Cabot, Marie-Odile Parat   +2 more
core   +2 more sources

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Startle sign events induced by mechanical manipulation during surgery for neuroma localization: a retrospective cohort study

BMC Anesthesiology
Background Chronic pain from peripheral neuromas is difficult to manage and often requires surgical excision, though intraoperative identification of neuromas can be challenging due to anatomical ambiguity.
Jonathan M. Gorky, Sarah J. Karinja, Sylvia L. Ranjeva, Lingshan Liu, Matthew R. Smith, Ariel L. Mueller, Timothy T. Houle, Kyle R. Eberlin, Katarina J. Ruscic   +8 more
doaj   +1 more source

General versus Spinal Anesthesia: Comparison of Complications and Outcomes in Lumbar Laminectomy Surgery [PDF]

Background: This study was designed to compare the complications and outcomes of lumbar laminectomy surgery performed by general and spinal anesthesia.
Hosein Taravati, Associate Professor, Department of Anesthesiology, Afzalipour Sc, Mohsen Shahba, Assistant Professor, Department of Neurosurgery , Afzalipour Sch, Reza Javdani, Resident, Department of Neurosurgery, Afzalipour School of Medic   +2 more
core  

EEG signals analysis using multiscale entropy for depth of anesthesia monitoring during surgery through artificial neural networks [PDF]

, 2015
In order to build a reliable index to monitor the depth of anesthesia (DOA), many algorithms have been proposed in recent years, one of which is sample entropy (SampEn), a commonly used and important tool to measure the regularity of data series. However,
Abbod, MF, Chen, YF, Fan, SZ, Liu, Q, Shieh, JS   +4 more
core   +4 more sources