Results 271 to 280 of about 6,840,055 (366)

Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis   +6 more
wiley   +1 more source

Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute   +5 more
wiley   +1 more source

Guided Bone Regeneration Membrane Materials Loaded with Chimeric Nanovesicles Promote Early Bone Defect Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang   +13 more
wiley   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark   +9 more
wiley   +1 more source

The impact of dental intervention under general anesthesia in Kohlschutter-Tonz Syndrome: a case series. [PDF]

open access: yesBMC Pediatr
Absawi MK   +6 more
europepmc   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li   +8 more
wiley   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy