Results 321 to 330 of about 7,756,484 (416)

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

open access: yesAdvanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf   +7 more
wiley   +1 more source

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

open access: yesAdvanced Science, EarlyView.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo   +17 more
wiley   +1 more source

Corneal Abrasions During General Anesthesia

open access: bronze, 1977
Yatindra Kumar Batra, INDER M. BALI
openalex   +1 more source

Adenosine Monophosphate Improves Lipolysis in Obese Mice by Reducing DNA Methylation via ADORA2A Activation by Ecto‐5′‐Nucleotidase (CD73)

open access: yesAdvanced Science, EarlyView.
In this study, the improvement effect of AMP on obesity can be attributed to the conversion of extracellular AMP to ADO through ADORA2A activation by CD73, which can promote lipolysis by reducing DNA methylation level and enhancing HSL gene transcription. These findings show the great potential of AMP in improving obesity.
Zhijuan Cui   +12 more
wiley   +1 more source

Incidental diagnosis of tracheal trifurcation detected during general anesthesia from Nepal: a case report. [PDF]

open access: yesAnn Med Surg (Lond)
Gaire S   +5 more
europepmc   +1 more source

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

open access: yesAdvanced Science, EarlyView.
Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang   +9 more
wiley   +1 more source

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