Results 131 to 140 of about 3,936,944 (293)

The use of an active learning approach in a SCALE-UP learning space improves academic performance in undergraduate General Biology. [PDF]

PLoS One, 2018
Hacisalihoglu G, Stephens D, Johnson L, Edington M.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Learning Gains from a Recurring "Teach and Question" Homework Assignment in a General Biology Course: Using Reciprocal Peer Tutoring Outside Class. [PDF]

CBE Life Sci Educ, 2018
Bailey EG, Baek D, Meiling J, Morris C, Nelson N, Rice NS, Rose S, Stockdale P.   +7 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Empowering the on-site detection of nucleic acids by integrating CRISPR and digital signal processing

Nature Communications
Addressing the global disparity in cancer care necessitates the development of rapid and affordable nucleic acid (NA) testing technologies. This need is particularly critical for cervical cancer, where molecular detection of human papillomavirus (HPV ...
Chang Yeol Lee, Hyunho Kim, Ismail Degani, Hanna Lee, Angel Sandoval, Yoonho Nam, Madeleine Pascavis, Hyun Gyu Park, Thomas Randall, Amy Ly, Cesar M. Castro, Hakho Lee   +11 more
doaj   +1 more source

General Biology and Current Management Approaches of Soft Scale Pests (Hemiptera: Coccidae). [PDF]

J Integr Pest Manag, 2015
Camacho ER, Chong JH.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Promoting an active form of learning out-of-class via answering online "study questions" leads to higher than expected exam scores in General Biology. [PDF]

PeerJ, 2015
Gibson SI.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Alternative Symmetries in Quantum Field Theory and Gravity

, 2011
A general, incomplete and partisan overview of various areas of the theoretical investigation is presented. Most of this activity stems from the search for physics beyond quantum field theory and general relativity, a titanic struggle that, in my opinion,
Iorio, Alfredo
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