Results 131 to 140 of about 13,799,383 (294)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Exploring Evolution and Biology of Oomycetes: Integrative and Comparative Genomics [PDF]

open access: yes, 2013
Diseases that destroy livestock and crops have had catastrophic effects on human civilization, causing starvation and economical losses and continue to be a constant threat to global food production.
Sub Theoretical Biology & Bioinformatics   +3 more
core  

Empowering the on-site detection of nucleic acids by integrating CRISPR and digital signal processing

open access: yesNature Communications
Addressing the global disparity in cancer care necessitates the development of rapid and affordable nucleic acid (NA) testing technologies. This need is particularly critical for cervical cancer, where molecular detection of human papillomavirus (HPV ...
Chang Yeol Lee   +11 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Story of a great Australian industry / Australian General Electric Limited.

open access: yes, 1937
Cover title.; Added title pages: The manufacturing activities of Australian General Electric Limited. With camera and pen through a great Australian industry.; Electronic reproduction. Canberra, A.C.T.
Australian General Electric Ltd.
core  

Psicología, biología y economía

open access: yesSuma de Negocios, 2011
Despite the close relationship between economics, biology and psychology since the late nineteenth century –the main economic categories have clear psychological connotations– the so called “mainstream” economics has not studied these links ...
Jorge Iván González
doaj  

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