Results 171 to 180 of about 11,347,707 (376)

Deep learning pipeline for automated cell profiling from cyclic imaging

Scientific Reports
Cyclic fluorescence microscopy enables multiple targets to be detected simultaneously. This, in turn, has deepened our understanding of tissue composition, cell-to-cell interactions, and cell signaling.
Christian Landeros, Juhyun Oh, Ralph Weissleder, Hakho Lee   +3 more
doaj   +1 more source

(1) Allgemeine Biologie: eine Einführung in die Lehre vom Leben (2) Outlines of General Zoology (3) A Text-Book of Biology: for Students in General, Medical and Technical Courses [PDF]

, 1925

openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

The Biology of Bacteria: an Introduction to General Microbiology [PDF]

, 1935
R. T. H.
openalex   +1 more source

An overview of gravitational physiology [PDF]

The focus of this review is on the response of humans and animals to the effects of the near weightless condition occurring aboard orbiting spacecraft. Gravity is an omnipresent force that has been a constant part of our lives and of the evolution of all
Miquel, Jaime, Souza, Kenneth A.
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress

Nature Communications
Non-coding 7SL RNA is an ancestor to mammalian Alu and B1 SINE RNAs and is thought to function exclusively within the Signal Recognition Particle (SRP), aiding in the translocation of secretory proteins into the endoplasmic reticulum for export. Here, we
Bojan Bujisic, Hun-Goo Lee, Lilei Xu, Uri Weissbein, Carlos Rivera, Ivan Topisirovic, Jeannie T. Lee   +6 more
doaj   +1 more source

Biology and a General University Education [PDF]

, 1955
W. B. Yapp
openalex   +1 more source

Africa: the FBA connection [PDF]

, 1986
Since its inception in the 1930's the Freshwater Biological Association at Windermere, England has been involved in research on African lakes and rivers.
Fryer, G., Talling, J.F.
core