Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
General and professional biology : with special reference to man
Edward John von Komorowski Menge
openalex +2 more sources
CONTENT OF METAPEDETIC KNOWLEDGE IN THE STUDY OF BIOLOGY AT THE LEVEL OF SECONDARY GENERAL EDUCATION [PDF]
M.A. Yakunchev+3 more
openalex +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Psicología, biología y economía
Despite the close relationship between economics, biology and psychology since the late nineteenth century –the main economic categories have clear psychological connotations– the so called “mainstream” economics has not studied these links ...
Jorge Iván González
doaj
Learning Gains from a Recurring "Teach and Question" Homework Assignment in a General Biology Course: Using Reciprocal Peer Tutoring Outside Class. [PDF]
Bailey EG+7 more
europepmc +1 more source
Dr. John C. Reed, Associate Editor of Cancer Biology and Therapy in the area of Apoptosis, is the Most Highly Cited Author in General Biomedicine from 1995-2005. [PDF]
openalex +1 more source
A Journey to Journal Writing: Significance of Non-Threatening Assessment in the Remedial Class of Grade 12 General Biology 1 Students [PDF]
Eduardo P. Santillan
openalex +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
Toward a General Theory for the Scaling and Universality of Thermal Responses in Biology [PDF]
We developed a theory showing that under appropriate normalizations and rescalings, temperature response curves show a remarkably regular behavior and follow a general, universal law. The impressive universality of temperature response curves remained hidden due to various curve-fitting models not well-grounded in first principles.
arxiv