Results 291 to 300 of about 11,347,707 (376)

Sex‐Related Differences in Efficacy and Safety Outcomes in Axial Spondyloarthritis Randomized Clinical Trials: A Systematic Literature Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao, Jordi Pardo Pardo, Steven Dang, Lianne S. Gensler, Philip Mease, Lihi Eder   +5 more
wiley   +1 more source

Ploidy plasticity drives fungal resistance to azoles used in agriculture and clinics. [PDF]

PLoS Biol
Sanyal K, Narayanan A.
europepmc   +1 more source

Association Between Metabolic Syndrome and Radiographic Changes in Psoriatic Arthritis: A Cohort Study

Arthritis Care &Research, EarlyView.
Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf, Shangyi Gao, S. Ercan Tunc, Justine Y. Ye, Daniel Pereira, Dafna D. Gladman, Vinod Chandran   +6 more
wiley   +1 more source

The coming wave of confluent biosynthetic, bioinformational and bioengineering technologies. [PDF]

Nat Commun
Pretorius IS, Dixon TA, Boers M, Paulsen IT, Johnson DL.   +4 more
europepmc   +1 more source

Juvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective This study compares trajectories of earnings and work loss in individuals with juvenile idiopathic arthritis (JIA) versus matched comparators from the general population. Methods Patients with JIA (n = 4,737) were identified in the Swedish National Patient Register (2001–2017) and individually matched to up to five general population ...
Heather Miller, Martin Neovius, Erik Sundberg, Johan Askling, Gustaf Bruze   +4 more
wiley   +1 more source

Edge-enhanced interaction graph network for protein-ligand binding affinity prediction. [PDF]

PLoS One
Yang D, Kuang L, Hu A.
europepmc   +1 more source

Diverse Treatment Goals in Psoriatic Arthritis: Insights from participants in the PARC cohort

Arthritis Care &Research, Accepted Article.
Objective The aim was to examine patient‐reported treatment goals among individuals with psoriatic arthritis (PsA). Methods Participants in the Psoriatic Arthritis Research Consortium (PARC) completed standardized assessments including patient‐reported outcome (PROs) instruments between 2017‐2020.
Astia Allenzara, Kat Bush, M. Elaine Husni, Soumya M. Reddy, Jose U. Scher, Ethan Craig, Joelle Koplin, Jessica A. Walsh, Alexis Ogdie   +8 more
wiley   +1 more source

Consideration of a Liquid Mutation-Accumulation Experiment to Measure Mutation Rates by Successive Serial Dilution. [PDF]

Genome Biol Evol
Baehr S, Ho WC, Perez S, Cenzano A, Hancock K, Patrick L, Brown A, Miller S, Lynch M.   +8 more
europepmc   +1 more source

The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review

Arthritis Care &Research, Accepted Article.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co‐morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C Scott   +3 more
wiley   +1 more source

Eleven quick tips for writing a Bioconductor package. [PDF]

PLoS Comput Biol
Soneson C, Shepherd L, Ramos M, Rue-Albrecht K, Rainer J, Pagès H, Carey VJ.   +6 more
europepmc   +1 more source