Results 81 to 90 of about 13,799,383 (294)

Synthetic Biology: Advancing Biological Frontiers by Building Synthetic Systems [PDF]

, 2012
Advances in synthetic biology are contributing to diverse research areas, from basic biology to biomanufacturing and disease therapy. We discuss the theoretical foundation, applications, and potential of this emerging field.Version of ...
Yvonne Y Chen, Chen, Yvonne Y., Smolke, Christina D, Smolke, Christina D., Chen, Yvonne Yu-Hsuan, Kate E Galloway, Christina D Smolke, Galloway, Kate E., Chen, Yvonne Y, Galloway, Kate E   +9 more
core   +1 more source

Contraloría General

, 2012
146 p.
Contraloría General, Contraloría General
core   +1 more source

Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents

Neoplasia: An International Journal for Oncology Research, 2012
A number of small-molecule poly (ADP-ribose) polymerase (PARP) inhibitors are currently undergoing advanced clinical trials. Determining the distribution and target inhibitory activity of these drugs in individual subjects, however, has proven ...
Thomas Reiner, Jessica Lacy, Edmund J. Keliher, Katherine S. Yang, Adeeti Ullal, Rainer H. Kohler, Claudio Vinegoni, Ralph Weissleder   +7 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Happy 100th, structural biology [PDF]

Structural Dynamics
About 100 years ago, the field of structural biology was born, led by James B. Sumner who recognized that enzymes were molecules with specific functions.
George N. Phillips, Jr., Eaton Edward Lattman   +1 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Experimental Biology & Communication

, 2023
This introductory biology laboratory course covers the application of experimental techniques in microbiology, biochemistry, cell and developmental biology.
Steiner, Lisa, Guarente, Leonard, RajBhandary, Uttam, King, Jonathan   +3 more
core   +1 more source

Exposure to endosulfan can cause long term effects on general biology, including the reproductive system of mice. [PDF]

Front Genet, 2022
Sharma A, Kaninathan A, Dahal S, Kumari S, Choudhary B, Raghavan SC.   +5 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source