Results 131 to 140 of about 1,115,871 (358)

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon   +10 more
wiley   +1 more source

Estimation of changes in runoff and its sources in response to future climate change in a critical zone of the Karakoram mountainous region, Pakistan in the near and far future

open access: yesGeomatics, Natural Hazards & Risk
The inconsistent pattern of precipitation, a shift in the seasonality of river flows, and the early onset of snow and glacier melt in recent decades across river basins of High Mountain Asia (HMA) has compelled us to further investigate future variations
Muhammad Adnan   +6 more
doaj   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

Midwinter suppression of baroclinic storm activity on Mars: observations and models [PDF]

open access: yes, 2011
We present results from assimilated analyses of observations from the Mars Global Surveyor Thermal Emission Spectrometer showing evidence for a regular suppression of baroclinic circumpolar storm activity in both hemispheres of Mars around winter ...
Lewis, S. R.   +3 more
core  

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

open access: yesAdvanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint   +6 more
wiley   +1 more source

A Three-dimensional Numerical Model for Baroclinic Dynamic in the Malacca Strait [PDF]

open access: yes, 2005
The circulation in the Malacca Strait is simulated using a three-dimensionalbaroclinic numerical model. The circulation model isderived from the combined effects of tides, wind, meteorologicalforcings, temperature and salinity.
al, T. I. (Taufiq)
core  

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

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