Results 141 to 150 of about 1,527,976 (335)

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

EXPERIMENTS WITH A STRATOSPHERIC GENERAL CIRCULATION MODEL III. LARGE-SCALE DIFFUSION OF OZONE INCLUDING PHOTOCHEMISTRY

, 1969
B. G. Hunt
openalex   +1 more source

Southern Oscillation: Further Studies with a GFDL General Circulation Model [PDF]

, 1983
R. N. Keshavamurty
openalex   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Evaluation of a general circulation model by the CERES Flux-by-cloud type simulator. [PDF]

J Geophys Res Atmos, 2017
Eitzen ZA, Su W, Xu KM, Loeb N, Sun M, Doelling D, Rose F, Bodas-Salcedo A.   +7 more
europepmc   +1 more source

Verification of General Circulation Models Applied to the Hamburg University GCM. Part I: Test of Individual Climate States [PDF]

, 1983
Hans von Storch, E. Roeckner
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Thermosphere-Ionosphere-Electrodynamics General Circulation Model for the Ionospheric Connection Explorer: TIEGCM-ICON. [PDF]

Space Sci Rev, 2017
Maute A.
europepmc   +1 more source

The Response of a Linear Model of the Tropical Pacific to Surface Winds from the NCAR General Circulation Model [PDF]

, 1989
Nicholas E. Graham, T. P. Barnett, Vijay Panchang, Ole Martin Smedstad, James J. O’Brien, Robert M. Chervin   +5 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source