Sensitivity of Late-Glacial and Holocene Climates to the Combined Effects of Orbital Parameter Changes and Lower Boundary Condition Changes: “Snapshot” Simulations with A General Circulation Model for 18, 9, AND 6 ka BP [PDF]
John E. Kutzbach, P. J. Guetter
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A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao+8 more
wiley +1 more source
Global Future Climate Signal by Latitudes Using CMIP6 GCMs
This study estimated global climate change signals at different latitudes for four main Shared Socioeconomic Pathways (SSPs). Five evaluation metrics were integrated using the Technique for Order of Preference by Similarity to Ideal Solution to quantify ...
Young Hoon Song+2 more
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Dynamic and Thermodynamic Influences of the Tibetan Plateau on the Atmosphere in a General Circulation Model [PDF]
Qinglin Zheng, Kuo‐Nan Liou
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Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Simulation of Airborne Impurity Cycles Using Atmospheric General Circulation Models [PDF]
Sylvie Joussaume
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A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
A Comparison of Baroclinic Instability with the Time Variations of Kinetic Energy in a General Circulation Model [PDF]
R. L. Walko, Robert Gall
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This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies+8 more
wiley +1 more source
A January Angular Momentum Balance in the OSU Two-Level Atmospheric General Circulation Model [PDF]
J.-W. Kim, W. Grady
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