Results 211 to 220 of about 1,527,976 (335)
Tropical Pacific Ocean response to observed winds in a layered general circulation model [PDF]
Arthur J. Miller+3 more
openalex +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Red blood cells with reduced deformability are selectively cleared from circulation in a mouse model. [PDF]
Islamzada E+5 more
europepmc +1 more source
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin+19 more
wiley +1 more source
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide+7 more
wiley +1 more source
Correlation of sdLDL-C and Apob with the degree of cerebral artery stenosis in posterior circulation stroke. [PDF]
Sun Z, Liu J, Wang A, Si Z.
europepmc +1 more source
Structure and predictability of the El Nino/Southern Oscillation phenomenon in a coupled ocean-atmosphere general circulation model [PDF]
openalex +1 more source
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun+13 more
wiley +1 more source
Effect of carotid artery stenosis on collateral flow status in patients with acute ischemic stroke after mechanical thrombectomy. [PDF]
Su JL, Xue DY, Wei XY, Yang XY.
europepmc +1 more source