From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini +2 more
wiley +1 more source
Reduced Emergency Department Visits and Hospitalizations in Infants after Universal Respiratory Syncytial Virus Immunization, Italy, 2024-25. [PDF]
Villa S +20 more
europepmc +1 more source
Models of temperature structure and general circulation
James B. Pollack
openalex +1 more source
Shapeshifting Liquid Metal Droplets for Soft Fluidic Machines
This study presented a liquid metal shape shifting strategy which harnesses Lorentz force, surface tension and fluid instabilities to achieve autonomous fluidic power. By using a liquid metal droplet as a mobile current carrier, this strategy enables the development of low‐voltage, self‐oscillating pumps that outperform existing soft pumps.
Saba Firouznia +5 more
wiley +1 more source
Evaluation of ChatGPT-5 for Automated ASPECTS Assessment on Non-Contrast CT in Acute Ischemic Stroke. [PDF]
Genez S +6 more
europepmc +1 more source
Downscaling of general circulation models using generative AI
Global Climate Models (GCMs) are an essential tool for projecting climate change impacts but theircoarse spatial resolution (often 100-200 km) limits their applicability for detailed climate assessments ona regional scale. This thesis develops a downscaling framework which combine a novel conditionalGenerative Adversarial Network (cGAN) with Quantile ...
openaire +1 more source
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
wiley +1 more source
Systemic immune-inflammation index associated with functional outcomes after endovascular thrombectomy in anterior circulation acute ischemic stroke. [PDF]
Han L +4 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Large-amplitude variability driven by giant dust storms on a planetary-mass companion. [PDF]
Tan X +19 more
europepmc +1 more source

