Results 271 to 280 of about 1,115,871 (358)

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

open access: yesAdvanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang   +8 more
wiley   +1 more source

Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats. [PDF]

open access: yesHypertension
Shi H   +8 more
europepmc   +1 more source

Resolution-dependent variations of sinking Lagrangian particles in general circulation models

open access: green, 2020
Peter Nooteboom   +5 more
openalex   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

open access: yesAdvanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez   +4 more
wiley   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

Cerebrovascular CTA radiomics for objective collateral grading in acute ischemic stroke. [PDF]

open access: yesEur Radiol Exp
Rallios D   +9 more
europepmc   +1 more source

Downscaling of general circulation models using generative AI

open access: yes
Global Climate Models (GCMs) are an essential tool for projecting climate change impacts but theircoarse spatial resolution (often 100-200 km) limits their applicability for detailed climate assessments ona regional scale. This thesis develops a downscaling framework which combine a novel conditionalGenerative Adversarial Network (cGAN) with Quantile ...
openaire   +1 more source

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