Results 21 to 30 of about 170,693 (311)

Relation of severe COVID-19 to polypharmacy and prescribing of psychotropic drugs: the REACT-SCOT case-control study

open access: yesBMC Medicine, 2021
Background The objective of this study was to investigate the relation of severe COVID-19 to prior drug prescribing. Methods Severe cases were defined by entry to critical care or fatal outcome.
Paul M. McKeigue   +17 more
doaj   +1 more source

Access to Leniency Documents and Actions for Damages – an Uneasy Match

open access: yesMarket and Competition Law Review, 2017
Directive 2014/104 of the European Parliament and the Council of 26 November 2014 (hereinafter Damages Directive) constitutes a first attempt to harmonize the actions for damages for infringement of competition law provisions both at national and ...
Krystyna Kowalik-Bańczyk
doaj   +1 more source

A New Derogation to the Admissibility of an Application in Staff Cases: The Cerafogli Judgment

open access: yesEuropean Papers, 2017
(Series Information) European Papers - A Journal on Law and Integration, 2016 1(3), 1301-1304 | European Forum Highlight of 5 January 2017 | (Abstract) On 27 October 2016, the Extended Composition of the Appeal Chamber of the GC rendered the judgment in ...
Massimo Francesco Orzan
doaj   +1 more source

Isolation and preservation of multipotent mesenchymal stem cells from bone marrow of Arabian leopard (Panthera pradus nimr) [PDF]

open access: yesOpen Veterinary Journal, 2018
The Arabian leopard (Panthera pardus nimr) is critically endangered by the International Union for Conservation of Nature, with an effective population of 150-250 across its entire range in the Arabian Peninsula. Isolation and preservation of multipotent
Andrzej Golachowski   +2 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Scientific Uncertainty before the Court of Justice and the General Court: Is the Judicial Toolbox Sufficient?

open access: yes, 2023
The uncertainty of empirical assertions is a pervasive problem in litigation before the EU Court of Justice (ECJ) and the General Court (EGC). It is particularly pressing in environmental law cases. At present, ‘science’ cannot be plausibly conceived of as a social practice generative of absolute and unchallengeable assertions but, rather, as a never ...
Eliantonio, Mariolina, Krajewski, Michal
openaire   +2 more sources

Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos   +5 more
wiley   +1 more source

A View from the General Court. The Reform for the Transfer of Competence for Preliminary Rulings to the General Court: Issues Concerning Its Implementation

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(2), 391-403 | Article | (Table of Contents) 1. Introduction. – 2. The partial transfer of jurisdiction in ‘certain specific areas’. – 3.
Ornella Porchia
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

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