Results 101 to 110 of about 1,880,777 (265)

General Education Teachers' Perceptions of Autism, Inclusive Practices, and Relationship Building Strategies. [PDF]

open access: yesJ Autism Dev Disord, 2022
Bolourian Y   +4 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

通識課程專業化芻議: 以問題意識和課程品質為取徑 A Brief Discussion of Professionalizing General Education: Approaching by Problem Awareness and Curriculum Quality

open access: yesJournal of Curriculum Studies
隨著政治民主和社會脈絡的變遷,臺灣的通識教育逐步發展和演變。從1958年教育部所頒布「共同必修科目」,直至1994年透過大法官會議解釋條文廢除相關規定,通識教育也經歷自由化與自主化的洗禮。然而,長期以來臺灣高等教育片面重視專業教育的效益,導致通識課程處於邊緣化或破碎化的危機。因此,建構通識教育的專業化具有重要性。本文以通識教育專業化的課程實踐案例,凸顯建構問題意識和深化課程品質的取徑,期能對於提升通識教育的課程品質及學術承載度發揮引導作用。讓臺灣的通識教育之發展與優化 ...
陳淑敏 Amy Shumin Chen   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

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