Results 61 to 70 of about 15,213 (267)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Response of Fractionally Damped Beams with General Boundary Conditions Subjected to Moving Loads
Shock and Vibration, 2012 This paper presents the transverse vibration of Bernoulli-Euler homogeneous isotropic damped beams with general boundary conditions. The beams are assumed to be subjected to a load moving at a uniform velocity.
R. Abu-Mallouh +3 more
doaj +1 more source
Entropy, 2018 In this paper, an anomalous advection-dispersion model involving a new general Liouville–Caputo fractional-order derivative is addressed for the first time.
Xin Liang +4 more
doaj +1 more source
Fractional Scale Calculus: Hadamard vs. Liouville
Fractal and Fractional, 2023 A general fractional scale derivative is introduced and studied. Its relation with the Hadamard derivatives is established and reformulated. A new derivative similar to the Grünwald–Letnikov’s is deduced. Tempered versions are also introduced.
Manuel D. Ortigueira, Gary W. Bohannan
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Optimal homotopy asymptotic method for solving several models of first order fuzzy fractional IVPs
Alexandria Engineering Journal, 2022 In this work, the Optimal Homotopy Asymptotic Method (OHAM) is prolifically implemented to find the optimal solutions of fractional order of fuzzy differential equations.
Dulfikar Jawad Hashim +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Generalized Brouncker’s continued fractions and their logarithmic derivatives [PDF]
The Ramanujan Journal, 2013 In this paper, we study the continued fraction y(s,r) which satisfies the equation y(s,r)y(s+2r,r)=(s+1)(s+2r-1) for r > 1/2. This continued fraction is a generalization of the Brouncker's continued fraction b(s). We extend the formulas for the first and the second logarithmic derivatives of b(s) to the case of y(s,r).
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source