Results 91 to 100 of about 5,170,464 (353)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Prevalence and consequences of patient safety incidents in general practice in the Netherlands: a retrospective medical record review study [PDF]

open access: yes, 2016
BACKGROUND Patient safety can be at stake in both hospital and general practice settings. While severe patient safety incidents have been described, quantitative studies in large samples of patients in general practice are rare.
Gaal, Sander   +5 more
core   +1 more source

When Suicide Is Not Suicide: Self-induced Morbidity and Mortality in the General Hospital

open access: yesRambam Maimonides Medical Journal, 2015
Suicidal phenomena in the general hospital can take a variety of forms that can be parsed by taking into account whether or not the patient 1) intended to hasten death, and 2) included collaborators, including family and health care providers, in the ...
J. Michael Bostwick
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Título: Cédula 1797 01 11 [PDF]

open access: yes
Esc. real en port.Sign.
Burguete, Francisco   +1 more
core   +1 more source

Teaching and learning evidence-based medicine: cross-sectional survey investigating knowledge and attitudes of teachers and learners in primary and secondary care [PDF]

open access: yes, 2007
Evidence-based medicine (EBM) is an important component of quality healthcare and a key part of the curriculum for doctors in training. There have been no previous studies comparing attitudes and knowledge of doctors in primary and secondary care ...
Gemmell, Islay   +3 more
core   +1 more source

Pengukuran Kualitas Pelayanan Rumah Sakit di Aceh dengan Model HSQ-Metrix

open access: yesJurnal Maksipreneur: Manajemen, Koperasi, dan Entrepreneurship, 2019
From the preliminary study, the results stated that there was a tendency for an increase in healthcare tourism of Acehnese visits to Malaysia from year to year. The chaotic condition represent of the quality of health services in Indonesia, especially in
Iwan Budhiarta, Muttaqin Samuthi
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

York General Hospital Auxiliary Records - Accession 145 [PDF]

open access: yes, 1979
The York County Hospital Auxiliary Records consist of correspondence, minutes, bylaws, reports, financial records, newsletters, newspaper clippings, and photographs relating to the activites and duties of the York General Hospital Auxiliary volunteer ...
York General Hospital Auxiliary
core   +1 more source

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