Results 101 to 110 of about 5,497,512 (352)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Associação entre depressão, níveis de dor e falta de apoio social em pacientes internados em enfermarias de clínica médica Association of depression, levels of pain and lack of social support in patients admitted to general medical wards

open access: yesJornal Brasileiro de Psiquiatria, 2013
OBJETIVO: Verificar a associação entre depressão, níveis de dor e falta de apoio social em pacientes clínicos internados. MÉTODOS: Em um estudo transversal, 1.147 adultos admitidos nas enfermarias de clínica médica de um hospital universitário foram ...
Camila Andrade Marques   +3 more
doaj  

Apoio psicológico na terminalidade: ensinamentos para a vida Apoyo psicológico en la terminalidad: enseñanzas para la vida Psychological support in terminality: a lesson for life

open access: yesPsicologia em Estudo, 2010
Em meio à crescente negação do sofrimento humano na contemporaneidade, a morte é cada vez mais banida do cotidiano e confinada aos hospitais. O presente trabalho tem por objetivo relatar uma experiência de intervenção psicológica junto a um paciente ...
Érika Arantes de Oliveira   +2 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

A Simplified “One-Pathway” Protocol for the Transformation of General Wards to Infectious Disease Wards Upon the Pandemic Outbreak

open access: yesFrontiers in Public Health, 2022
Jikai Yin   +5 more
doaj   +1 more source

Behavior Assessment in Children Following Hospital-Based General Anesthesia versus Office-Based General Anesthesia [PDF]

open access: gold, 2016
LaQuia A. Vinson   +6 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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