Results 101 to 110 of about 5,170,464 (353)

Predicators of Satisfaction and Dissatisfaction of Medical Workers with Their Work in Medical Institution [PDF]

, 2017
The resulting criterion of assessment of staff management effectiveness in health protection institution is a satisfaction of medical workers with their work.
Moskalenko, M. (Maksym), Pariy, V. (Valentyn), Vezhnovets, T. (Tetyana), Vyshnyvetskyy, I. (Ivan)   +3 more
core   +2 more sources

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

An optimized methodology for whole genome sequencing of RNA respiratory viruses from nasopharyngeal aspirates [PDF]

, 2018
Over the last decade, the number of viral genome sequences deposited in available databases has grown exponentially. However, sequencing methodology vary widely and many published works have relied on viral enrichment by viral culture or nucleic acid ...
Goya, Stephanie, Greninger, Alexander L., Marti, Marcelo Adrian, Mistchenko, Alicia Susana, Nabaes Jodar, Mercedes Soledad, Rojo, Gabriel Lihue, Tittarelli, Estefanía, Valinotto, Laura Elena, Viegas, Mariana, Zaiat, Jonathan Javier   +9 more
core   +2 more sources

The psychiatrist and the general hospital

Comprehensive Psychiatry, 1963
Summary Over a period of 21 months, 319 patients were seen in a general hospital for a psychiatric assessment. Details are given of emergency referrals and attempted suicides, and the special problems encountered in medical, surgical, obstetrical and gynecologic cases are discussed.
F.E. Kenyon, M.L. Rutter
openaire   +3 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Finding Aid for Rochester General Hospital [PDF]

Finding Aid for the Rochester General Hospital Collection. Rochester General Hospital is located in Rochester, New York. Record groups include: Rochester Female Charitable Society; Women\u27s Board; Rochester General Hospital Association; Twigs; RCH ...
Rochester General Hospital
core   +1 more source

A staff training intervention to improve communication between people living with dementia and health-care professionals in hospital: the VOICE mixed-methods development and evaluation study

Health Services and Delivery Research, 2018
Background: Twenty-five per cent of hospital beds are occupied by a person living with dementia. Dementia affects expressive communication and understanding. Health-care professionals report a lack of communication skills training.
Rowan H Harwood, Rebecca O’Brien, Sarah E Goldberg, Rebecca Allwood, Alison Pilnick, Suzanne Beeke, Louise Thomson, Megan Murray, Ruth Parry, Fiona Kearney, Bryn Baxendale, Kate Sartain, Justine Schneider   +12 more
doaj   +1 more source