Results 111 to 120 of about 15,812,427 (330)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
A General Equilibrium Model of the Term Structure of Interest Rates under Regime-switching Risk [PDF]
This paper incorporates the systematic risk of regime shifts into a general equilibrium model of the term structure of interest rates. The model shows that there is a new source of time-variation in bond term premiums in the presence of regime shifts ...
Shu Wu, Yong Zeng
core
How can we measure Scotland’s footprint? (and, once we have, what do we do with it?) [PDF]
, 2008 Recent months have seen a great deal of interest and consultation in Scotland regarding environmental and carbon accounting in general, and the calculation and use of ecological and carbon footprints in particular.
Turner, Karen
core
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Services of general interest in the European Union
Derecho PUCP, 2016 (i) Since the eighties, the European Union has implemented a policy aimed to achieve that the services of general economic interest are truly integrated in the internal market.
José Carlos Laguna de Paz
doaj
Interest rate rules vs. money growth rules: a welfare comparison in a cash-in-advance economy [PDF]
A consideration of the welfare consequences of two simple monetary policy rules--an interest rate peg and a money growth peg--in a dynamic general-equilibrium model, indicating that the interest rate rule dominates the money growth rule.Monetary ...
Charles T. Carlstrom, Timothy S. Fuerst
core
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
General Public Interest: between Electoral Rhetoric and Administrative Actions
Journal of Danubian Studies and Research, 2012 Traditionally, public administration is considered to be the operative side of government. Itis supposed to include all the activities involved in carrying out the policies of the elected officialsand some activities associated with the development of ...
Valentina Cornea
doaj