Results 111 to 120 of about 10,127,947 (331)
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
International factor mobility, informal interest rate and capital market imperfection: a general equilibrium analysis [PDF]
This paper makes a pioneering attempt to provide a theory of determination of interest rate in the informal credit market in a small open economy in terms of a three-sector general equilibrium model. There are two informal sectors which obtain production
Chaudhuri, Sarbajit+1 more
core +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
General Public Interest: between Electoral Rhetoric and Administrative Actions
Traditionally, public administration is considered to be the operative side of government. Itis supposed to include all the activities involved in carrying out the policies of the elected officialsand some activities associated with the development of ...
Valentina Cornea
doaj
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Imaging SNAREs at work in ‘unroofed’ cells – approaches that may be of general interest for functional studies on membrane proteins [PDF]
Thorsten Lang
openalex +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Governing growth in organic farming: The evolving capacities of organic groups in the United Kingdom and Denmark [PDF]
The question of the ‘policy capacity’ of interest groups is increasingly gaining prominence as a key variable in governing and transformative capacities. This raises the issue of whether group policy capacities can be developed. While group scholars have
Daugbjerg, Carsten, Halpin, Darren
core
The Romanian Administrative Code represents the main outcome of the project “A more coherent legislative framework for a more efficient public administration”, financed through the Operational Programme for the Development of the Administrative Capacity ...
Domnica FOCŞĂNEANU+3 more
doaj
Wojtek J. Krzanowski, Donald Preece
openaire +2 more sources