Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention
ABSTRACT Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid‐beta (Aβ) PET retention is low. A 63‐year‐old woman presenting with a 3‐year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI.
Ryosuke Shimasaki+5 more
wiley +1 more source
Shallow endoscopic submucosal dissection using a gas-free immersion system to prevent strictures after esophageal dissections. [PDF]
Nomura T+6 more
europepmc +1 more source
Evaluation of Surgical Excision of Basal Cell Carcinoma by General Practitioners with Special Interest (GPwSI) within Community Dermatology Clinics [PDF]
Mohammed Al Abadie
openalex +1 more source
Response to Letter to the Editor Regarding the Article Entitled 'The Safety of Spinal Surgery in Patients over 80 Years of Age: Propensity Score Matching Study' by Bang C et al. [PDF]
Bang C, Kim YH.
europepmc +1 more source
Transition to Circular Economy and Management of Public Services of General Economic Interest
Sandra Antoniazzi
openalex +1 more source
Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1
ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano+15 more
wiley +1 more source
The Effect of Establishment of an Integrated Plastic Surgery Program on General Surgery Resident Fellowship Aspirations. [PDF]
Krasner H+6 more
europepmc +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Deciphering hematopoietic stem cell heterogeneity: breakthroughs in functional subpopulations and molecular markers. [PDF]
Lei Y, Guo M, Ai H.
europepmc +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte+23 more
wiley +1 more source