Results 61 to 70 of about 3,690,653 (268)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Legal, Administrative and Managerial Aspects of the Civil Service
Acta Universitatis Danubius: Administratio, 2012 The main objective of this article is to identify and capture the defining notion of the public function available within the Romanian and foreign doctrines.
Victor Alistar
doaj
Estimating DSGE Model with Zero Real Interest Rate Policy on Iran's Economy [PDF]
سیاستگذاری اقتصادیPurpose: The Central Bank, as the organ in charge of monetary policies, implements those policies that achieve the selected final goals. In order to achieve these goals, central banks usually use a mechanism.
Ali Nazari +3 more
doaj +1 more source
The general interest in running and walking has increased during the COVID-19. [PDF]
Acta Biomed, 2023 Mattiuzzi C, Lippi G.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Enfoque perioperatorio de la insuficiencia suprarrenal en el contexto de un paciente con síndrome poliglandular: Reporte de caso [PDF]
Revista Chilena de Anestesia, 2022 Luz Adriana Galindo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Training Models for General Practitioners with Special Interests: Foreign Experiences and Chinese Insights [PDF]
Zhongguo quanke yixueCultivating excellent general practitioners is an important guarantee for promoting their role as "gatekeepers" of the population's health, and sub-specialty training for general practitioners is an important measure for bridging the gap ...
CUI Longyan, DAI Gaolanxin, TAO Hongbing
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source