Results 151 to 160 of about 1,452,737 (303)
A semi-analytical approach for analysis of laminated plates with general boundary conditions under a general distribution of loads is developed. The non-linear equations are solved by the Newton-Kantorovich-Quadrature (NKQ) method which is a combination ...
Rasoul Khandan +4 more
doaj
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Asymptotic Regularity of a Generalised Stochastic Halpern Scheme. [PDF]
Pischke N, Powell T.
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Covariate adjustment in randomized clinical trials: From general theory to practical insights. [PDF]
Bannick MS, Yi Y, Ye T.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Nonlinear KCCA in fMRI activation analysis: Self-supervised optimization and robust back-reconstruction. [PDF]
Han C, Yang Z, Zhuang X, Cordes D.
europepmc +1 more source
GENERALIZED LINEAR METHODS AND CONVERGENCE ACCELERATION
openaire +4 more sources

