Results 41 to 50 of about 58,240 (249)

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

An Interpretable Two-Phase Modeling Approach for Lung Cancer Survivability Prediction

Sensors, 2022
Although lung cancer survival status and survival length predictions have primarily been studied individually, a scheme that leverages both fields in an interpretable way for physicians remains elusive. We propose a two-phase data analytic framework that
Zahra Sedighi-Maman, Jonathan J. Heath
doaj   +1 more source

Retrospective power analysis

, 2009
The pdf contains the article; the ASCII file contains SAS code to calculate power and confidence limits for simple linear regression, as detailed in the article appendix.Many papers have appeared in the recent biological literature encouraging us to ...
Thomas, Len
core   +1 more source

The General Linear Model: theory and practicalities in brain morphometric analyses [PDF]

, 2018
The general linear model (GLM) is the statistical method of choice used in brain morphometric analyses because of its ability to incorporate a multitude of effects.
Pernet, Cyril R, Cyril R. Pernet
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Identification of putative markers linked to grain plumpness in rice (Oryza sativa L.) via association mapping

BMC Genetics, 2017
Background Poor grain plumpness (GP) is one of the main constraints to reaching the yield potential of hybrid rice. Results In this study, the GP of 177 rice varieties was investigated in three locations across 2 years.
Erbao Liu, Siyuan Zeng, Xiangong Chen, Xiaojing Dang, Lijun Liang, Hui Wang, Zhiyao Dong, Yang Liu, Delin Hong   +8 more
doaj   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Robust statistical methods and the credibility movement of psychological science [PDF]

PeerJ
The general linear model (GLM) is the most frequently applied family of statistical models in psychology. Within the GLM, the effects under study are estimated using the ordinary least squares (OLS) estimation.
Martina Sladekova, Andy P. Field
doaj   +2 more sources

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Evaluating methods for measuring background connectivity in slow event‐related functional magnetic resonance imaging designs

Brain and Behavior, 2023
Introduction Resting‐state functional magnetic resonance imaging (fMRI) is widely used for measuring functional interactions between brain regions, significantly contributing to our understanding of large‐scale brain networks and brain–behavior ...
Lea E. Frank, Dagmar Zeithamova
doaj   +1 more source