Results 41 to 50 of about 58,672 (256)

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

Predicting the Aqueductal Cerebrospinal Fluid Pulse: A Statistical Approach

Applied Sciences, 2019
The cerebrospinal fluid (CSF) pulse in the Aqueduct of Sylvius (aCSF pulse) is often used to evaluate structural changes in the brain. Here we present a novel application of the general linear model (GLM) to predict the motion of the aCSF pulse.
Clive B Beggs, Simon J Shepherd, Pietro Cecconi, Maria Marcella Lagana   +3 more
doaj   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Efficiency of local minima and GLM techniques in sinkhole extraction from a LiDAR-based terrain model

International Journal of Digital Earth, 2019
The aim of this paper was to study reliable automated delineation possibilities of karst sinkholes using a LiDAR-based digital terrain model (DTM) with pixel-based classifications.
Péter Enyedi, Melinda Pap, Zoltán Kovács, László Takács-Szilágyi, Szilárd Szabó   +4 more
doaj   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Contributory Factors of Traffic Accidents in Lahore Using Generalized Linear Models (GLM)

NUST Journal of Engineering Sciences, 2019
The geometric design of roads is the branch of highway engineering concerned with the positioning of the physical elements of the roadway according to standards and limitations with objectives to optimize efficiency and safety while minimizing cost and environmental damage.
Hajra Slam, Yasar Mahmood
openaire   +3 more sources

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Adapting the Insurance Pricing Model for Distribution Channel Expansion Using the Bayesian Generalized Linear Model [PDF]

Operations Research and Decisions
The insurance market is changing due to new distribution channels, requiring insurers to update their pricing models. We propose a mathematical approach using Bayesian generalized linear models (GLM) to adjust insurance pricing. Our strategy modifies the
Carina Gunawan, Muhamad Ivan Faizal, Nanang Susyanto   +2 more
doaj  

autohrf-an R package for generating data-informed event models for general linear modeling of task-based fMRI data

Frontiers in Neuroimaging, 2022
The analysis of task-related fMRI data at the level of individual participants is commonly based on general linear modeling (GLM), which allows us to estimate the extent to which the BOLD signal can be explained by the task response predictors specified ...
Nina Purg, Jure Demšar, Jure Demšar, Alan Anticevic, Alan Anticevic, Grega Repovš   +5 more
doaj   +1 more source

Non-Convex Penalized Estimation of Count Data Responses via Generalized Linear Model (GLM)

Asian Journal of Fuzzy and Applied Mathematics, 2020
This study provided a non-convex penalized estimation procedure via Smoothed Clipped Absolute Deviation (SCAD) and Minimax Concave Penalty (MCP) for count data responses to checkmate the problem of covariates exceeding the sample size . The Generalized Linear Model (GLM) approach was adopted in obtaining the penalized functions needed by the MCP and ...
Rasaki Olawale Olanrewaju, Johnson Funminiyi Ojo   +1 more
openaire   +2 more sources